Non-motor features of Parkinson disease

AHV Schapira, KR Chaudhuri, P Jenner - Nature Reviews …, 2017 - nature.com
Many of the motor symptoms of Parkinson disease (PD) can be preceded, sometimes for
several years, by non-motor symptoms that include hyposmia, sleep disorders, depression …

[HTML][HTML] Prevalence and clinical aspects of depression in Parkinson's disease: a systematic review and meta‑analysis of 129 studies

S Cong, C Xiang, S Zhang, T Zhang, H Wang… - … & Biobehavioral Reviews, 2022 - Elsevier
Depression is one of the most important non-motor symptoms in Parkinson's disease (PD),
but its prevalence and related clinical characteristics are unclear. To this end, we performed …

Current treatment options for Alzheimer's disease and Parkinson's disease dementia

J YY Szeto, S JG Lewis - Current neuropharmacology, 2016 - ingentaconnect.com
Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common
neurodegenerative disorders encountered in clinical practice. Whilst dementia has long …

Alzheimer's disease–related dementias summit 2016: National research priorities

RA Corriveau, WJ Koroshetz, JT Gladman, S Jeon… - Neurology, 2017 - AAN Enterprises
Goal 1 of the National Plan to Address Alzheimer's Disease is to prevent and effectively treat
Alzheimer disease and Alzheimer disease–related dementias by 2025. To help inform the …

The mechanisms of action of deep brain stimulation and ideas for the future development

K Udupa, R Chen - Progress in neurobiology, 2015 - Elsevier
Deep brain stimulation (DBS) has been used as a treatment of movement disorders such as
Parkinson's disease, dystonia, and essential tremor for over twenty years, and is a promising …

[HTML][HTML] Weight loss and malnutrition in patients with Parkinson's disease: current knowledge and future prospects

K Ma, N Xiong, Y Shen, C Han, L Liu… - Frontiers in aging …, 2018 - frontiersin.org
Parkinson's Disease (PD) is currently considered a systemic neurodegenerative disease
manifested with not only motor but also non-motor symptoms. In particular, weight loss and …

[HTML][HTML] Risk factors for cognitive impairment in patients with type 2 diabetes

L Sun, X Diao, X Gang, Y Lv, X Zhao, S Yang… - Journal of diabetes …, 2020 - hindawi.com
Objectives. To investigate the risk factors for cognitive impairment in Chinese type 2
diabetes mellitus (T2DM) patients of advanced age and to identify effective biomarkers of …

[HTML][HTML] Ambroxol as a novel disease-modifying treatment for Parkinson's disease dementia: Protocol for a single-centre, randomized, double-blind, placebo …

CRA Silveira, J MacKinley, K Coleman, Z Li, E Finger… - BMC neurology, 2019 - Springer
Background Currently there are no disease-modifying treatments for Parkinson's disease
dementia (PDD), a condition linked to aggregation of the protein α-synuclein in subcortical …

[HTML][HTML] Approach to cognitive impairment in Parkinson's disease

Q Zhang, GM Aldridge, NS Narayanan, SW Anderson… - …, 2020 - Elsevier
Cognitive dysfunction is common in Parkinson's disease (PD) and predicts poor clinical
outcomes. It is associated primarily with pathologic involvement of basal forebrain …

Impacts of dance on non-motor symptoms, participation, and quality of life in Parkinson disease and healthy older adults

ME McNeely, RP Duncan, GM Earhart - Maturitas, 2015 - Elsevier
Evidence indicates exercise is beneficial for motor and non-motor function in older adults
and people with chronic diseases including Parkinson disease (PD). Dance may be a …