There are several reports describing the sonographic sign of a thickened nuchal fold for the
prenatal sonographic detection of Down syndrome in the second trimester. We prospectively …

Objective. To evaluate skeletal abnormalities on post-mortem radiographs of fetuses with
Down's syndrome. Materials and methods. Biometrical and morphological criteria, which are …

Objective: This study was undertaken to assess the value of minor ultrasonographic markers
in predicting significant karyotypic abnormalities. Study Design: A total of 2743 fetuses (14 …

A prospective analysis investigating the associations between pathogenic copy number
variations (pCNVs) and ultrasound soft markers (USMs) in fetuses and evaluating the …

Objective To investigate the role of first trimester sonography in detecting chromosomal
abnormalities in an unselected obstetric population. Methods 2281 women (mean maternal …

Up till the early 1970s, prenatal diagnosis of congenital anomalies was primarily aimed at
detecting chromosomal abnormalities by amniocentesis. 1. Over the last two decades …

This study evaluated women's understanding of prenatal ultrasound in terms of meeting the
requirements for informed choice. A cross-sectional survey was conducted to evaluate (1) …

Sonographic markers for Down's syndrome have been useful in the identification of affected
fetuses. In this study, we evaluated the accuracy of an expanded scoring index that included …

The most effective sonographic marker of trisomy 21 and other chromosomal defects is
increased nuchal translucency (NT) thickness at 11–14 weeks. Extensive studies over the …

Background: We aimed to assess the clinical application of noninvasive prenatal screening
(NIPS) based on second-trimester ultrasonographic soft markers (USMs) in low-risk …