OBJECTIVE: To determine the sensitivity and specificity of soft-tissue nuchal-fold
measurement in the second-trimester fetus for the detection of trisomy 21. METHOD: Thirty …

Although it is widely accepted that the best time to screen for chromosomal abnormalities is
the first trimester, ultrasound evaluation of the fetus in the second trimester has also been …

Neural tube defects (NTDs) are among the most common major congenital malformations in
most countries. Striking variations in incidence have been known for years, with extremely …

This book is a catalog of detailed information on approximately 800 conditions that have
been diagnosed prenatally. It includes the methods of detecting fetal abnormalities, the …

Ultrasound evidence for aneuploidy may be found in almost every organ of the fetus and can
be used to modify the risk of aneuploidy. The diagnosis of these minor anomalies on second …

OBJECTIVE: The purpose of this study was to compare the efficiency of second-trimester
nasal bone hypoplasia (NB) and increased nuchal fold (NF) in Down syndrome screening …

Objectives and methods: To investigate the impact of prenatal diagnosis on trisomy 21 live
births, we collected all prenatal and postnatal trisomy 21 cases (n= 1096) in the eastern half …

The discovery in the mid‐1970s that maternal serum maternal serum a‐fetoprotein (AFP)
levels are increased on average in pregnancies affected by fetal neural tube defects (NTDs) …

Objective The aim of our study was to evaluate whether the combined use of umbilical artery
pulsatility index (UAPI) and nuchal translucency (NT) measurements would be useful in the …

目的探讨妊娠11~ 14 周, 胎儿颈项透明层厚度(NT)≥ 3mm 时与其染色体异常的相关性.
方法对73 例胎儿颈项透明层厚度≥ 3mm 的孕妇行早期胎儿绒毛或中期羊水穿刺取样 …