Zwitterionic biomaterials

Q Li, C Wen, J Yang, X Zhou, Y Zhu, J Zheng… - Chemical …, 2022 - ACS Publications
The term “zwitterionic polymers” refers to polymers that bear a pair of oppositely charged
groups in their repeating units. When these oppositely charged groups are equally …

[HTML][HTML] A comparative review of natural and synthetic biopolymer composite scaffolds

MSB Reddy, D Ponnamma, R Choudhary… - Polymers, 2021 - mdpi.com
Tissue engineering (TE) and regenerative medicine integrate information and technology
from various fields to restore/replace tissues and damaged organs for medical treatments …

A strain-programmed patch for the healing of diabetic wounds

G Theocharidis, H Yuk, H Roh, L Wang… - Nature biomedical …, 2022 - nature.com
Diabetic foot ulcers and other chronic wounds with impaired healing can be treated with
bioengineered skin or with growth factors. However, most patients do not benefit from these …

[HTML][HTML] Engineering the next generation of cell-based therapeutics

CJ Bashor, IB Hilton, H Bandukwala… - Nature Reviews Drug …, 2022 - nature.com
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …

[HTML][HTML] Foreign body reaction to implanted biomaterials and its impact in nerve neuroprosthetics

A Carnicer-Lombarte, ST Chen… - … in Bioengineering and …, 2021 - frontiersin.org
The implantation of any foreign material into the body leads to the development of an
inflammatory and fibrotic process—the foreign body reaction (FBR). Upon implantation into a …

DAMPs, PAMPs, and LAMPs in immunity and sterile inflammation

J Zindel, P Kubes - Annual Review of Pathology: Mechanisms of …, 2020 - annualreviews.org
Recognizing the importance of leukocyte trafficking in inflammation led to some therapeutic
breakthroughs. However, many inflammatory pathologies remain without specific therapy …

Hydrogels in the clinic

A Mandal, JR Clegg, AC Anselmo… - Bioengineering & …, 2020 - Wiley Online Library
Injectable hydrogels are one of the most widely investigated and versatile technologies for
drug delivery and tissue engineering applications. Hydrogels' versatility arises from their …

[HTML][HTML] Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

Dealing with the foreign‐body response to implanted biomaterials: strategies and applications of new materials

D Zhang, Q Chen, C Shi, M Chen, K Ma… - Advanced Functional …, 2021 - Wiley Online Library
Foreign‐body response caused by implanted biomaterials seriously impedes the function of
implants and is a major obstacle to the development of implantable biomaterials and …

The multifaceted roles of macrophages in bone regeneration: a story of polarization, activation and time

C Schlundt, H Fischer, CH Bucher, C Rendenbach… - Acta biomaterialia, 2021 - Elsevier
To present knowledge, macrophages are found in all tissues of the human body. They are a
cell population with high plasticity which come with a multitude of functions which appear to …