Co‐translational Installation of Posttranslational Modifications by Non‐canonical Amino Acid Mutagenesis
Protein posttranslational modifications (PTMs) play critical roles in regulating cellular
activities. Here we provide a survey of genetic code expansion (GCE) methods that were …
activities. Here we provide a survey of genetic code expansion (GCE) methods that were …
[HTML][HTML] Dual stop codon suppression in mammalian cells with genomically integrated genetic code expansion machinery
B Meineke, J Heimgärtner, R Caridha, MF Block… - Cell Reports …, 2023 - cell.com
Stop codon suppression using dedicated tRNA/aminoacyl-tRNA synthetase (aaRS) pairs
allows for genetically encoded, site-specific incorporation of non-canonical amino acids …
allows for genetically encoded, site-specific incorporation of non-canonical amino acids …
Translation in a Box: Orthogonal Evolution in the Saccharomyces cerevisiae Mitochondrion
B Rothschild-Mancinelli, C Alvarez-Carreño, W Guo… - bioRxiv, 2023 - biorxiv.org
The ability to re-engineer and creatively evolve the translation system (TS) would allow
invention of new coded polymers by altering the amino acid sidechain inventory and by …
invention of new coded polymers by altering the amino acid sidechain inventory and by …
Xenobiology in synthetic biology: From non-standard amino acid incorporation to biosecurity implications
S Vinke - 2023 - pub.uni-bielefeld.de
In the era of sustainability, synthetic biology has emerged as a game changing field, holding
immense potential to create innovative solutions to restore the ecological balance. The …
immense potential to create innovative solutions to restore the ecological balance. The …