NAE modulators: a potential therapy for gastric carcinoma
Q Liang, M Liu, J Li, R Tong, Y Hu, L Bai… - European Journal of …, 2022 - Elsevier
Neural precursor cell expressed developmentally downregulated protein-8 (NEDD8) is a
ubiquitin-like protein, which activates an important post-translational modification process …
ubiquitin-like protein, which activates an important post-translational modification process …
Cullin-Ring Ligases as promising targets for gastric carcinoma treatment
Q Song, S Feng, W Peng, A Li, T Ma, B Yu… - Pharmacological …, 2021 - Elsevier
Gastric carcinoma has serious morbidity and mortality, which seriously threats human
health. The studies on gastrointestinal cell biology have shown that the ubiquitination …
health. The studies on gastrointestinal cell biology have shown that the ubiquitination …
CUL4B enhances the malignant phenotype of esophageal squamous cell carcinoma by suppressing TGFBR3 expression
Q Gong, Y Wang, K Zhu, X Bai, T Feng, G Sun… - Biochemical and …, 2023 - Elsevier
Abstract Cullin 4B (CUL4B), which acts as a scaffold protein in CUL4B-RING ubiquitin ligase
complexes (CRL4B), is frequently overexpressed in cancer and represses tumor …
complexes (CRL4B), is frequently overexpressed in cancer and represses tumor …
Update on molecular biomarkers for diagnosis and prediction of prognosis and treatment responses in gastric cancer
M Sasahara, M Kanda, Y Kodera - 2021 - digitum.um.es
Gastric cancer (GC) is one of the leading causes of cancer-related deaths worldwide, and its
high mortality rate is a serious problem in many regions. To improve prognosis, it is …
high mortality rate is a serious problem in many regions. To improve prognosis, it is …
CUL4B is a potential novel prognostic biomarker and is correlated with immune infiltrates in malignant pleural mesothelioma
L Liu, R Hui, T Zeng, X Yang, Q Wu… - International Journal of …, 2022 - Taylor & Francis
Background Malignant pleural mesothelioma (MPM) is a particularly fatal cancer with a
median survival of less than one year. The value of single-agent checkpoint inhibitors is still …
median survival of less than one year. The value of single-agent checkpoint inhibitors is still …