Molecular diagnosis of drug-resistant tuberculosis; a literature review

TNA Nguyen, V Anton-Le Berre, AL Bañuls… - Frontiers in …, 2019 - frontiersin.org
Drug-resistant tuberculosis is a global health problem that hinders the progress of
tuberculosis eradication programs. Accurate and early detection of drug-resistant …

Mechanisms and detection methods of Mycobacterium tuberculosis rifampicin resistance: The phenomenon of drug resistance is complex

G Xu, H Liu, X Jia, X Wang, P Xu - Tuberculosis, 2021 - Elsevier
Tuberculosis (TB) is an infectious disease that poses a serious threat to human health.
Rifampin (RIF) is an important first-line anti-TB drug, and rifampin resistance (RIF-R) is a key …

Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

AL Manson, KA Cohen, T Abeel, CA Desjardins… - Nature …, 2017 - nature.com
Multidrug-resistant tuberculosis (MDR-TB), caused by drug-resistant strains of
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …

An insight into advances in developing nanotechnology based therapeutics, drug delivery, diagnostics and vaccines: multidimensional applications in tuberculosis …

H Chopra, YK Mohanta, PR Rauta, R Ahmed… - Pharmaceuticals, 2023 - mdpi.com
Tuberculosis (TB), one of the deadliest contagious diseases, is a major concern worldwide.
Long-term treatment, a high pill burden, limited compliance, and strict administration …

Diagnosis of tuberculosis in HIV co‐infected individuals: current status, challenges and opportunities for the future

P Méndez‐Samperio - Scandinavian journal of immunology, 2017 - Wiley Online Library
Tuberculosis (TB) remains one of the most important causes of death among people co‐
infected with human immunodeficiency virus (HIV). The diagnosis of TB remains challenging …

Rapid molecular assays for the diagnosis of drug-resistant tuberculosis

L Nandlal, R Perumal, K Naidoo - Infection and Drug Resistance, 2022 - Taylor & Francis
The recognition that drug-resistant tuberculosis (DR-TB) poses a major threat to global
tuberculosis (TB) control efforts has catalysed the development of new and urgently needed …

Accuracy of an amplicon-sequencing nanopore approach to identify variants in tuberculosis drug-resistance-associated genes

C Mariner-Llicer, GA Goig… - Microbial …, 2021 - microbiologyresearch.org
A rapid and accurate diagnostic assay represents an important means to detect
Mycobacterium tuberculosis, identify drug-resistant strains and ensure treatment success …

Diagnosis of opportunistic infections: HIV co-infections–tuberculosis

L Scott, P da Silva, CC Boehme… - Current Opinion in …, 2017 - journals.lww.com
In this review, we describe diagnostic strategies specifically for HIV and TB co-infected
individuals. Molecular diagnostics in particular within the past 5 years have revolutionized …

Evaluation of the Abbott RealTime MTB and RealTime MTB INH/RIF Assays for Direct Detection of Mycobacterium tuberculosis Complex and Resistance Markers in …

S Hofmann-Thiel, N Molodtsov… - Journal of clinical …, 2016 - Am Soc Microbiol
ABSTRACT The Abbott RealTi me MTB (RT MTB) assay is a new automated nucleic acid
amplification test for the detection of Mycobacterium tuberculosis complex (MTBC) in clinical …

Molecular Diagnostics for Mycobacterium tuberculosis Infection

KV Dicks, JE Stout - Annual Review of Medicine, 2019 - annualreviews.org
Resistance to antimycobacterial drugs is a major barrier to effective treatment of
Mycobacterium tuberculosis infection. Molecular diagnostic techniques based on the …