[HTML][HTML] The biology of SCUBE

YC Lin, BK Sahoo, SS Gau, RB Yang - Journal of biomedical science, 2023 - Springer
Abstract The SCUBE [Signal peptide-Complement C1r/C1s, Uegf, Bmp1 (CUB)-Epithelial
growth factor domain-containing protein] family consists of three proteins in vertebrates …

[HTML][HTML] Oncogenic roles of LINC01234 in various forms of human cancer

M Kong, X Yu, Q Zheng, S Zhang, W Guo - Biomedicine & …, 2022 - Elsevier
Abnormal expression of long non-coding RNAs (lncRNAs) plays an essential role in various
malignant neoplasia. As a newly identified lncRNA, LINC01234 is abnormally expressed in …

Identification of a potential signature to predict the risk of postmenopausal osteoporosis

Y Geng, R Shao, T Xu, L Zhang - Gene, 2024 - Elsevier
Background Postmenopausal osteoporosis (PMOP) is related to the elevated risk of fracture
in postmenopausal women. Thus, to effectively predict the occurrence of PMOP, we …

LncRNA CARMN Affects Hepatocellular Carcinoma Prognosis by Regulating the miR‐192‐5p/LOXL2 Axis

X Wang, S Wu, Y Yang, J Zhao - Oxidative Medicine and …, 2022 - Wiley Online Library
Background. Hepatocellular carcinoma (HCC) is aggressive cancer with a poor prognosis. It
has been suggested that the aberrant expression of LOXL2 is associated with the …

SCUBE3 exerts a tumor-promoting effect in tongue squamous cell carcinoma by promoting CEBPA binding to the CCL2 promoter

M Zhu, Y Ma, W Wang, M Li, S Chen, F Liu, X Shi… - Molecular Cancer …, 2024 - AACR
Tongue squamous cell carcinoma (TSCC) is the main pathologic subtype of oral cancer, and
the current therapeutic effect is far from satisfactory. The signal peptide-CUB-EGF domain …

[HTML][HTML] JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation

J Wang, L Liu, Z Li, H Wang, Y Ren, K Wang, Y Liu… - BMC genomics, 2024 - Springer
Background In epigenetic modification, histone modification and DNA methylation
coordinate the regulation of spermatogonium. Not only can methylcytosine dioxygenase 1 …

β-catenin/TCF4-induced SCUBE3 upregulation promotes ovarian cancer development via HIF-1 signaling pathway

J Shen, X Ma, Z Wei, Q Qian, A Jing, Y Ding… - Molecular and Cellular …, 2024 - Elsevier
The precise involvement and mechanistic role of the signal peptide-CUB-EGF-like domain-
containing protein 3 (SCUBE3) in ovarian cancer (OV) remain poorly understood. Here …

CircSCUBE3 reduces the anti-gastric cancer activity of anti-PD-L1

HS Shan, XB Zhang, X Zhang, YT Wei, LL Meng… - Molecular …, 2024 - Springer
The progression of gastric cancer (GC) is closely related to tumor immune escape. The
research, therefore, studied the impact of possible circRNAs on the immune escape of GC …

[HTML][HTML] Targeting SCUBE3 in Hepatocellular Carcinoma

T Liu, X Yang, K Wang, Q Luo - Journal of Cellular Signaling, 2023 - scientificarchives.com
HCC is one of the most common malignant tumors. The life and health of humans are
gravely threatened by HCC because of its hidden onset, high recurrence rate, poor …

ECEL1 could be a gene involved in the cell proliferation and apoptosis in hepatocellular carcinoma

L Nie, KB Zou, YY Wang, Y Zuo, Q Chen, JW Long… - 2023 - researchsquare.com
Background: The expression and role of the endothelin converting Enzyme like1 (ECEL1)
gene in hepatocellular carcinoma (HCC) was unclear. The purpose of this study was to …