Importance Mendelian randomization (MR) is a statistical approach that has become
increasingly popular in the field of cardiovascular disease research. It offers a way to infer …

Background The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) is a
multinational collaborative research study with> 10,000 collaborators around the world. GBD …

Takayasu arteritis (TAK) refractory to conventional disease-modifying anti-rheumatic drugs
(DMARDs) is commonly treated with biologic DMARDs such as tocilizumab or tumor …

Aims We aim to investigate the association of the Dietary Inflammatory Index (DII) with the
prevalence of hypertension in a large multiracial population in the United States. Methods …

BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Bicuspid aortic valve is the most common congenital heart disease and exposes patients to
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …

Aims This study aims to outline the 'true'natural history of ascending thoracic aortic
aneurysm (ATAA) based on a cohort of patients not undergoing surgical intervention …

Background: Perioperative stroke remains a devastating complication in the operative
treatment of acute type A aortic dissection. To reduce the risk of perioperative stroke …

Objectives To define and compare growth rates of the distal aorta in Marfan patients with
and without aortic root replacement using serial MR angiography (MRA). Methods We …

Background Differences in the clinical course of heritable thoracic aortic disease based on
the disease‐causing gene have not been fully evaluated. To clarify the clinical relevance of …