Prime editing: advances and therapeutic applications
Z Zhao, P Shang, P Mohanraju, N Geijsen - Trends in Biotechnology, 2023 - cell.com
Clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR–
Cas)-mediated genome editing has revolutionized biomedical research and will likely …
Cas)-mediated genome editing has revolutionized biomedical research and will likely …
Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges
Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed
biomedical research and provided entirely new models to analyze every aspect of …
biomedical research and provided entirely new models to analyze every aspect of …
Biomaterial-assisted targeted and controlled delivery of CRISPR/Cas9 for precise gene editing
RISPR-Cas9 has exhibited enormous potential in gene therapy. It can perform genome
editing with single-nucleotide precision in various types of cell and tissue, providing a …
editing with single-nucleotide precision in various types of cell and tissue, providing a …
In vivo delivery of CRISPR-Cas9 genome editing components for therapeutic applications
Since its mechanism discovery in 2012 and the first application for mammalian genome
editing in 2013, CRISPR-Cas9 has revolutionized the genome engineering field and created …
editing in 2013, CRISPR-Cas9 has revolutionized the genome engineering field and created …
Immunogenicity of CRISPR therapeutics—Critical considerations for clinical translation
R Ewaisha, KS Anderson - Frontiers in Bioengineering and …, 2023 - frontiersin.org
CRISPR offers new hope for many patients and promises to transform the way we think of
future therapies. Ensuring safety of CRISPR therapeutics is a top priority for clinical …
future therapies. Ensuring safety of CRISPR therapeutics is a top priority for clinical …
[HTML][HTML] The biomedical potential of tardigrade proteins: A review
Tardigrades are ubiquitous microinvertebrates exhibiting extreme tolerance to various
environmental stressors like low and high temperatures, lack of water, or high radiation …
environmental stressors like low and high temperatures, lack of water, or high radiation …
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies
Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …
most dynamic and plastic tissues in the human body and plays a vital role in movement …
Viral Vectors, Exosomes, and Vexosomes: Potential armamentarium for delivering CRISPR/Cas to cancer cells
M Farzanehpour, A Miri, AG Alvanegh… - Biochemical …, 2023 - Elsevier
The underlying cause of cancer is genetic disruption, so gene editing technologies,
particularly CRISPR/Cas systems can be used to go against cancer. The field of gene …
particularly CRISPR/Cas systems can be used to go against cancer. The field of gene …
Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing
The CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 genome
editing system has been a major technological breakthrough that has brought revolutionary …
editing system has been a major technological breakthrough that has brought revolutionary …
Biomaterials-mediated CRISPR/Cas9 delivery: recent challenges and opportunities in gene therapy
AK Dubey, E Mostafavi - Frontiers in Chemistry, 2023 - frontiersin.org
The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …
holds tremendous potential. This innovative approach combines the advantages of …