Effective treatment of high blood pressure (BP) represents a key strategy for reducing the
burden of hypertension-related cardiovascular and renal diseases. In spite of these well …

Several types of calcium antagonists (CA)(verapamil, diltiazem, nifedipine and related
drugs) may be used as antihypertensives. In practice, the dihydropyridines (nifedipine and …

Synopsis Lacidipine is an orally administered calcium channel blocker of the
dihydropyridine class, which shows selectivity for vascular smooth muscle over cardiac …

Summary Abstract Lacidipine (Caldine®, Lacimen®, Lacipil®, Midotens®, Motens®) is a
once-daily, orally-administered, lipophilic dihydropyridine calcium antagonist with an …

Background Chronic heart failure (CHF) has high morbidity and mortality rates despite
treatment with angiotensin-converting enzyme inhibitors, diuretics, and digoxin. Adjunctive …

The selectivity of action of the clinically available calcium channel antagonists depends on a
number of factors: 1) Mode of calcium mobilization—intracellular and extracellular sources …

Essential hypertension is a complex clinical condition, characterized by multiple and
concomitant abnormal activation of different regulatory and contra-regulatory …

A 51-year-old man with a history of hypertensive and ischaemic myocardiopathy (cardiac
infarction 11 years ago), osteoarthritis and hypothyroidism, was treated daily with lacidipine …

Der zweite Band des Gebietes Drogen der Neuauflage enthält in alphabetischer
Reihenfolge von EO Monographien über Arzneipflanzengattungen. Jede Monographie …

The aim of the present study was to investigate virtual population pharmacokinetic using
physiologically based pharmacokinetic (PBPK) model for evaluating bioequivalence of oral …