The hypotensive effects of YM430 (4 (((S)-2-hydroxy-3-phenoxypropyl) amino) butyl methyl
2, 6-dimethyl-((S)-4-(m-nitrophenyl))-l, 4-dihydropyridine-3, 5-dicarboxylate) were evaluated …

Aim The effect of lacidipine for patients with essential hypertension and its effect on plasma
endothelin and angiotensin Ⅱ level were observed. Methods Forty patients with essential …

The study was conducted to find the influence of lacidipine (Ca2+ channel blocker, which is
widely used for hypertension) on the hypoglycemic activity of metformin (Biguanide …

Effective treatment of high blood pressure (BP) represents a key strategy for reducing the
burden of hypertension-related cardiovascular and renal diseases. In spite of these well …

Lacidipin wird gastrointestinal gut resorbiert, unterliegt jedoch einem ausgeprägten
präsystemischen Metabolismus. Seine biologische Verfügbarkeit beträgt lediglich 2 bis 9 …

2. Godfraind T, Salomone S (1991) Functional interaction of lacidipine with calcium
channeIs in vascular smooth musde. J Cardiovasc Pharmacol 18 Suppl II: S 1-S6 3. Micheli …

A series of studies which have utilised the euglycaemic hyperinsulinaemic clamp to
measure insulin sensitivity is described. The methods for measuring insulin sensitivity have …

In our recent review of calcium antagonists for the treatment of patients with cardiovascular
disease we concluded that most patients could be managed with formulations of one of the …