Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or
more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic …

Cardiovascular disease is an important cause for morbidity and mortality worldwide.
Flavonoids, such as naringin, and naringenin are important natural phytochemicals in the …

Flavonoids are important natural compounds with diverse biologic activities. Citrus
flavonoids constitute an important series of flavonoids. Naringin and its aglycone naringenin …

The antioxidant ability is the link and bridge connecting a variety of biological activities.
Citrus flavonoids play an essential role in regulating oxidative stress and are an important …

Homeostasis of nutrient metabolism is critical for maintenance of the normal physiologic
status of the cell and the integral health of humans and mammals. In vivo, there is a highly …

Polyphenols have long been recognized as health-promoting entities, including beneficial
effects on cardiovascular disease, but their reputation has been boosted recently following a …

Naringin, chemically 4′, 5, 7-trihydroxyflavanone-7-rhamnoglucoside, is a major flavanone
glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. It has been …

Obesity-related oxidative stress, the imbalance between pro-oxidants and antioxidants (eg,
nitric oxide), has been linked to metabolic and cardiovascular disease, including endothelial …

There is a need for continued drug development for nonalcoholic steatohepatitis (NASH).
Bergamot is a plant whose fruit juice is enriched with flavonoids and phenolic compounds …

Purpose Dysfunction of endothelial cells plays a key role in the pathogenesis of diabetic
atherosclerosis. High glucose (HG) has been found as a key factor in the progression of …