[HTML][HTML] Perivascular spaces as a potential biomarker of Alzheimer's disease
M Lynch, W Pham, B Sinclair, TJ O'Brien… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a highly damaging disease that affects one's cognition and
memory and presents an increasing societal and economic burden globally. Considerable …
memory and presents an increasing societal and economic burden globally. Considerable …
[HTML][HTML] Why are perivascular spaces important?
T Shulyatnikova, MR Hayden - Medicina, 2023 - mdpi.com
Perivascular spaces (PVS) and their enlargement (EPVS) have been gaining interest as
EPVS can be visualized non-invasively by magnetic resonance imaging (MRI) when viewing …
EPVS can be visualized non-invasively by magnetic resonance imaging (MRI) when viewing …
Correlation of glymphatic system abnormalities with Parkinson's disease progression: a clinical study based on non-invasive fMRI
JC Meng, MQ Shen, YL Lu, HX Feng, XY Chen… - Journal of …, 2024 - Springer
Background The glymphatic system is reportedly involved in Parkinson's disease (PD).
Based on previous studies, we aimed to confirm the correlation between the glymphatic …
Based on previous studies, we aimed to confirm the correlation between the glymphatic …
[HTML][HTML] Brain Endothelial Cells Play a Central Role in the Development of Enlarged Perivascular Spaces in the Metabolic Syndrome
MR Hayden - Medicina, 2023 - mdpi.com
Brain capillary endothelial cell (s)(BECs) have numerous functions, including their
semipermeable interface-barrier (transfer and diffusion of solutes), trophic (metabolic …
semipermeable interface-barrier (transfer and diffusion of solutes), trophic (metabolic …
Diffusion tensor image analysis ALong the perivascular space (DTI-ALPS): revisiting the meaning and significance of the method
The ALPS-index was found to be an indicator of a number of conditions related to the
glymphatic system. Thus, although this was expected in the original report, the results of the …
glymphatic system. Thus, although this was expected in the original report, the results of the …
[HTML][HTML] Sleep disorders and Alzheimer's disease pathophysiology: The role of the Glymphatic System. A scoping review
K Astara, A Tsimpolis, K Kalafatakis… - Mechanisms of Ageing …, 2023 - Elsevier
Background Alzheimer's disease (AD) is highly intertwined with sleep disturbances
throughout its whole natural history. Sleep consists of a major compound of the functionality …
throughout its whole natural history. Sleep consists of a major compound of the functionality …
Imaging Interstitial Fluid with MRI: A Narrative Review on the Associations of Altered Interstitial Fluid with Vascular and Neurodegenerative Abnormalities
GS Drenthen, EP Elschot… - Journal of Magnetic …, 2023 - Wiley Online Library
Interstitial fluid (ISF) refers to the fluid between the parenchymal cells and along the
perivascular spaces (PVS). ISF plays a crucial role in delivering nutrients and clearing waste …
perivascular spaces (PVS). ISF plays a crucial role in delivering nutrients and clearing waste …
The Alzheimer's Disease Neuroimaging Initiative in the era of Alzheimer's disease treatment: A review of ADNI studies from 2021 to 2022
DP Veitch, MW Weiner, M Miller, PS Aisen… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) aims to improve
Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging …
Alzheimer's disease (AD) clinical trials. Since 2006, ADNI has shared clinical, neuroimaging …
[HTML][HTML] High pulse wave velocity is associated with enlarged perivascular spaces in dementia with Lewy bodies
N Saji, Y Kinjo, K Murotani, S Niida, A Takeda… - Scientific Reports, 2024 - nature.com
Previous studies have demonstrated associations between enlarged perivascular spaces
(EPVS) and dementias such as Alzheimer's disease. However, an association between …
(EPVS) and dementias such as Alzheimer's disease. However, an association between …
Enlarged perivascular spaces and age-related clinical diseases
Y Yang, M Wang, M Luan, X Song, Y Wang… - … Interventions in Aging, 2023 - Taylor & Francis
Perivascular spaces are the fluid-filled areas surrounding small blood vessels in the brain,
and they may play a role similar to lymphatic vessels in clearing metabolic waste. When their …
and they may play a role similar to lymphatic vessels in clearing metabolic waste. When their …