In recent decades, mosquito-borne illnesses have emerged as a major health burden in
many tropical regions. These diseases, such as malaria, dengue fever, chikungunya, yellow …

The therapeutic potential of immunoglobulin M (IgM) is of considerable interest in
immunotherapy due to its complement-activating and cell-agglutinating abilities …

A major determinant of pathogenicity in malaria caused by Plasmodium falciparum is the
adhesion of parasite-infected erythrocytes to the vasculature or tissues of infected …

Plasmodium falciparum Erythrocyte Membrane Protein 1 (Pf EMP1) and Knob-associated
Histidine-rich Protein (KAHRP) are directly linked to malaria pathology. Pf EMP1 and …

Over 30 million women living in P. falciparum endemic areas are at risk of developing
malaria during pregnancy every year. Placental malaria is characterized by massive …

The quest for immune correlates of protection continues to slow vaccine development. To
date, only vaccine-induced antibodies have been confirmed as direct immune correlates of …

The malaria parasite has for long been thought to escape host complement attack as a
survival strategy. However, it was only recently that complement evasion mechanisms of the …

Nanoparticle tracking analysis (NTA) is an important technique for measuring hydrodynamic
size of globular biological particles including liposomes and viruses. Less attention has …

The complement system exerts crucial functions both in innate immune responses and
adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen …

PfEMP1 is a family of adhesive proteins expressed on the surface of Plasmodium falciparum-
infected erythrocytes (IEs), where they mediate adhesion of IEs to a range of host receptors …