[HTML][HTML] Predicting the effect of single mutations on protein stability and binding with respect to types of mutations

P Pandey, SK Panday, P Rimal, N Ancona… - International Journal of …, 2023 - mdpi.com
The development of methods and algorithms to predict the effect of mutations on protein
stability, protein–protein interaction, and protein–DNA/RNA binding is necessitated by the …

[HTML][HTML] Most monogenic disorders are caused by mutations altering protein folding free energy

P Pandey, E Alexov - International Journal of Molecular Sciences, 2024 - mdpi.com
Revealing the molecular effect that pathogenic missense mutations have on the
corresponding protein is crucial for developing therapeutic solutions. This is especially …

Predicting the Effect of Mutations on Protein Stability and Binding: Assessment of Leading Algorithms Performance and Databases Content with Respect to Types of …

P Pandey, S Pandey, P Rimal, N Ancona, E Alexov - 2023 - preprints.org
Abstract Development of methods and algorithms to predict the effect of mutations on protein
stability, protein-protein, and protein-DNA/RNA binding is necessitated by the needs of …