Cells release membrane enclosed nano-sized vesicles termed extracellular vesicles (EVs)
that function as mediators of intercellular communication by transferring biological …

Two broad categories of extracellular vesicles (EVs), exosomes and shed microvesicles
(sMVs), which differ in size distribution as well as protein and RNA profiles, have been …

Intercellular communication was long thought to be regulated exclusively through direct
contact between cells or via release of soluble molecules that transmit the signal by binding …

Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …

Extracellular vesicles (EVs) represent a novel mechanism of intercellular communication as
vehicles for intercellular transfer of functional membrane and cytosolic proteins, lipids, and …

The participation of extracellular vesicles in many cellular processes, including reproduction,
is unquestionable. Although currently, the tetraspanin proteins found in extracellular vesicles …

Tetraspanins are a family of proteins with four transmembrane domains that play a role in
many aspects of cell biology and physiology; they are also used by several pathogens for …

Tetraspanins are molecular scaffolds that distribute proteins into highly organized
microdomains consisting of adhesion, signaling, and adaptor proteins. Many reports have …

Cargo sorting to intraluminal vesicles (ILVs) of multivesicular endosomes is required for
lysosome-related organelle (LRO) biogenesis. PMEL—a component of melanocyte LROs …

Exosomes are discussed as potent therapeutics due to efficient transfer of proteins, mRNA
and miRNA in selective targets. However, therapeutic exosome application requires …