Background: In medicinal chemistry, thiazoles have gained great importance in antifungal
and anticancer drug design and development. Objectives: The aim of this study was to …

A series of thiosemicarbazides with 4-nitrophenyl group was obtained in the reaction of
carboxylic acid hydrazides with isothiocyanates. All compounds were checked for their …

Objectives Cancer is one of the leading causes of death throughout the world. Current
therapy options suffer from the major limitations of side effects and drug resistance. Thus …

In order to take the advantages of the anticancer properties of benzimidazoles and
hydrazones, we synthesized new 4‐(5‐chloro‐1 H‐benzimidazol‐2‐yl)‐benzoic acid …

A series of novel 2-phenyl-4-trifluoromethyl thiazole-5-carboxamide derivatives have been
synthesized and evaluated for their anticancer activity against A-549, Bel7402, and HCT-8 …

Asthma is a chronic, complex and heterogeneous inflammatory illness, characterized by
obstruction of the lower airways. About 334 million people worldwide suffer from asthma …

The reaction of divalent transition metal salts and (E)-N'-(1-(pyridin-2-yl) ethylidene)
nicotinohydrazide (penh) led to the formation of [Mn (penh) 2](complex 1),[Co (penh) …

Background: Hydrazones, frequently occurring motifs in many bioactive molecules, have
attracted a great deal of interest as potent antimicrobial agents. Objective: The aim of this …

Background: In recent years, the relationship between overexpression of matrix
metalloproteinases (MMPs) and tumor invasion/metastasis has prompted researchers to …

In the present study, nineteen new fluoro-benzimidazole derivatives, including nifuroxazide
analogs, were synthesized by microwave-supported reactions and tested against a panel of …