[HTML][HTML] Eliminating the breast cancer surgery paradigm after neoadjuvant systemic therapy: current evidence and future challenges

J Heil, HM Kuerer, A Pfob, G Rauch, HP Sinn… - Annals of …, 2020 - Elsevier
Highlights•Safe past de-escalation treatments.•Surgery after complete response might be
overtreatment.•Biopsies might diagnose response.In patients with operable early breast …

Advances in systemic therapies for triple negative breast cancer

RA Leon-Ferre, MP Goetz - Bmj, 2023 - bmj.com
Triple negative breast cancer (TNBC) continues to be the subtype of breast cancer with the
highest rates of recurrence and mortality. The lack of expression of targetable proteins such …

Eliminating breast surgery for invasive breast cancer in exceptional responders to neoadjuvant systemic therapy: a multicentre, single-arm, phase 2 trial

HM Kuerer, BD Smith, S Krishnamurthy… - The lancet …, 2022 - thelancet.com
Background Neoadjuvant systemic therapy (NST) for triple-negative breast cancer and
HER2-positive breast cancer yields a pathological complete response in approximately 60 …

Long-term standard sentinel node biopsy after neoadjuvant treatment in breast cancer: a single institution ten-year follow-up

S Kahler-Ribeiro-Fontana, E Pagan, F Magnoni… - European Journal of …, 2021 - Elsevier
Introduction In patients with positive lymph nodes (cN+) prior to neoadjuvant treatment
(NAT), which convert to a clinically negative axilla (cN0) after treatment, the use of sentinel …

The clinical significance of breast-only and node-only pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT): a review of 20,000 breast cancer …

OM Fayanju, Y Ren, SM Thomas, RA Greenup… - Annals of …, 2018 - journals.lww.com
Objective: To determine whether the association between overall survival (OS) and
response to neoadjuvant chemotherapy (NACT) in breast cancer patients varies with tumor …

Factors affecting pathologic complete response following neoadjuvant chemotherapy in breast cancer: development and validation of a predictive nomogram

SY Kim, N Cho, Y Choi, SH Lee, SM Ha, ES Kim… - Radiology, 2021 - pubs.rsna.org
Background There is an increasing need to develop a more accurate prediction model for
pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) in breast …

[HTML][HTML] Modern surgical treatment of breast cancer

M Riis - Annals of medicine and surgery, 2020 - Elsevier
Breast cancer is the most frequent cancer in women all over the world. The prognosis is
generally good, with a five-year overall survival rate above 90% for all stages. It is still the …

[HTML][HTML] Minimally invasive complete response assessment of the breast after neoadjuvant systemic therapy for early breast cancer (MICRA trial): interim analysis of a …

AA van Loevezijn, MEM van der Noordaa… - Annals of surgical …, 2021 - Springer
Background The added value of surgery in breast cancer patients with pathological
complete response (pCR) after neoadjuvant systemic therapy (NST) is uncertain. The …

[HTML][HTML] A machine learning model that classifies breast cancer pathologic complete response on MRI post-neoadjuvant chemotherapy

EJ Sutton, N Onishi, DA Fehr, BZ Dashevsky… - Breast Cancer …, 2020 - Springer
Background For breast cancer patients undergoing neoadjuvant chemotherapy (NAC),
pathologic complete response (pCR; no invasive or in situ) cannot be assessed non …

Accuracy of post–neoadjuvant chemotherapy image-guided breast biopsy to predict residual cancer

MK Tasoulis, HB Lee, W Yang, R Pope… - JAMA …, 2020 - jamanetwork.com
Importance Image-guided breast biopsy of a residual imaging abnormality or tumor bed after
neoadjuvant chemotherapy (NACT) is increasingly used to assess residual cancer, facilitate …