Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy

CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …

A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research

V Yadav, A Krishnan, D Vohora - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Piper longum, commonly referred as 'Pippali', has found its
traditional use in India, Malaysia, Singapore and other South Asian countries as an …

[HTML][HTML] Panax ginseng as an adjuvant treatment for Alzheimer's disease

HJ Kim, SW Jung, SY Kim, IH Cho, HC Kim… - Journal of ginseng …, 2018 - Elsevier
Longevity in medicine can be defined as a long life without mental or physical deficits. This
can be prevented by Alzheimer's disease (AD). Current conventional AD treatments only …

[HTML][HTML] Amelioration of colitis progression by ginseng-derived exosome-like nanoparticles through suppression of inflammatory cytokines

J Kim, S Zhang, Y Zhu, R Wang, J Wang - Journal of Ginseng Research, 2023 - Elsevier
Background Damage to the healthy intestinal epithelial layer and regulation of the intestinal
immune system, closely interrelated, are considered pivotal parts of the curative treatment …

Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and …

Y Chen, D Wang, H Peng, X Chen, X Han, J Yu… - Molecular Cancer, 2019 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is one of the most lethal
malignancies. Neovascularization during tumorigenesis supplies oxygen and nutrients to …

Prognostic value of platelet-to-lymphocyte ratio in pancreatic cancer: a comprehensive meta-analysis of 17 cohort studies

Y Zhou, S Cheng, AH Fathy, H Qian… - OncoTargets and …, 2018 - Taylor & Francis
Background and aims Several studies were conducted to explore the prognostic value of
platelet-to-lymphocyte ratio (PLR) in pancreatic cancer and have reported contradictory …

Roles of plant‐derived bioactive compounds and related microRNAs in cancer therapy

H Zou, Y Li, X Liu, Z Wu, J Li, Z Ma - Phytotherapy Research, 2021 - Wiley Online Library
Plant‐derived bioactive compounds, often called phytochemicals, are active substances
extracted from different plants. These bioactive compounds can release therapeutic potential …

Effects of compound K, an enteric microbiome metabolite of ginseng, in the treatment of inflammation associated colon cancer

H Yao, JY Wan, J Zeng, WH Huang… - Oncology …, 2018 - spandidos-publications.com
Ginsenoside Rb1, a major component of different ginseng species, can be bioconverted into
compound K by gut microbiota, and the latter possess much stronger cancer …

Pharmacological effects of natural medicine ginsenosides against Alzheimer's disease

Z Shi, H Chen, X Zhou, W Yang, Y Lin - Frontiers in Pharmacology, 2022 - frontiersin.org
Ginsenosides are the most important pharmacological active ingredient of ginseng, with
multiple biological therapeutic targets, mild action and no side effects. It is having shown …

New Insights into the Mechanisms of Chinese Herbal Products on Diabetes: A Focus on the “Bacteria‐Mucosal Immunity‐Inflammation‐Diabetes” Axis

Z Gao, Q Li, X Wu, X Zhao, L Zhao… - Journal of Immunology …, 2017 - Wiley Online Library
Diabetes, especially type 2, has been rapidly increasing all over the world. Although many
drugs have been developed and used to treat diabetes, side effects and long‐term efficacy …