[HTML][HTML] Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy
M Krampera, K Le Blanc - Cell stem cell, 2021 - cell.com
An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
[HTML][HTML] Priming approaches to improve the efficacy of mesenchymal stromal cell-based therapies
NC Noronha, A Mizukami, C Caliári-Oliveira… - Stem cell research & …, 2019 - Springer
Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …
[HTML][HTML] Advancing application of mesenchymal stem cell-based bone tissue regeneration
F Shang, Y Yu, S Liu, L Ming, Y Zhang, Z Zhou, J Zhao… - Bioactive materials, 2021 - Elsevier
Reconstruction of bone defects, especially the critical-sized defects, with mechanical
integrity to the skeleton is important for a patient's rehabilitation, however, it still remains …
integrity to the skeleton is important for a patient's rehabilitation, however, it still remains …
Biological functions of mesenchymal stem cells and clinical implications
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
[HTML][HTML] Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine
FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …
their capacity for local engrafting and differentiating into multiple tissue types. However …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles: toward cell-free therapeutic applications
Mesenchymal stem (stromal) cells (MSCs) are multipotent cells with the ability to differentiate
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …
into several cell types, thus serving as a cell reservoir for regenerative medicine. Much of the …
Challenges in clinical development of mesenchymal stromal/stem cells: concise review
I Mastrolia, EM Foppiani, A Murgia… - Stem cells …, 2019 - academic.oup.com
Identified 50 years ago, mesenchymal stromal/stem cells (MSCs) immediately generated a
substantial interest among the scientific community because of their differentiation plasticity …
substantial interest among the scientific community because of their differentiation plasticity …
Developing biodegradable lipid nanoparticles for intracellular mRNA delivery and genome editing
Conspectus Since the US Food and Drug Administration (FDA) granted emergency use
authorization for two mRNA vaccines against SARS-CoV-2, mRNA-based technology has …
authorization for two mRNA vaccines against SARS-CoV-2, mRNA-based technology has …
Human umbilical cord mesenchymal stem cells: a new era for stem cell therapy
The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs).
Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster …
Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster …
[HTML][HTML] Tissue source determines the differentiation potentials of mesenchymal stem cells: a comparative study of human mesenchymal stem cells from bone marrow …
Abstract Background Mesenchymal stem cells (MSCs) possess intrinsic regeneration
capacity as part of the repair process in response to injury, such as fracture or other tissue …
capacity as part of the repair process in response to injury, such as fracture or other tissue …