Lupus nephritis (LN) is a frequent and severe manifestation of SLE. Along the decades, the
epidemiology of LN and its clinical presentation have been changing. However, even …

Background In adults with active lupus nephritis, the efficacy and safety of intravenous
belimumab as compared with placebo, when added to standard therapy (mycophenolate …

Systemic lupus erythematosus (SLE) is an autoimmune multisystem disease with numerous
clinical manifestations. There is no consensus about the ideal oral management for this …

Autoimmune mediated inflammation and renal damage in lupus nephritis (LN) depends
partly on the infiltration of lymphocytes in glomeruli and renal interstitium. Here we identified …

Introduction The gold standard for diagnosis of active lupus nephritis (ALN), a kidney biopsy,
is invasive with attendant morbidity and cannot be serially repeated. Urinary ALCAM …

Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical
manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more …

Whether a repeat renal biopsy is helpful during lupus nephritis (LN) flares remains
debatable. In order to analyze the clinical utility of repeat renal biopsy in this complex …

Objective: To define predictors of response, time to response, flares, and long-term renal
outcome in an inception cohort of proliferative lupus nephritis (PLN). Methods: We included …

Background Repeated renal flares in lupus nephritis (LN) have been associated with worse
long-term kidney function. This study aimed to assess the impact of repeated LN flares in …

Recently, there has been emerging concern that crescents, the main histologic feature of
Henoch–Schönlein purpura nephritis, merely reflect active inflammation, and may not be …