Mitochondrial dysfunction and DNA damage in the context of pathogenesis of atherosclerosis

T Shemiakova, E Ivanova, AV Grechko, EV Gerasimova… - Biomedicines, 2020 - mdpi.com
Atherosclerosis is a multifactorial disease of the cardiovascular system associated with
aging, inflammation, and oxidative stress. An important role in the development of …

Role of the intestinal microbiome and its therapeutic intervention in cardiovascular disorder

A Luqman, A Hassan, M Ullah, S Naseem… - Frontiers in …, 2024 - frontiersin.org
The gut microbiome is a heterogeneous population of microbes comprising viruses,
bacteria, fungi, and protozoa. Such a microbiome is essential for sustaining host equilibrium …

Oxidative stress and antioxidant pathway in allergic rhinitis

M Han, D Lee, SH Lee, TH Kim - Antioxidants, 2021 - mdpi.com
Oxidative stress is the cause and consequence of redox metabolism in various physiological
and pathological conditions. Understanding the molecular pathways underlying oxidative …

[HTML][HTML] Pivotal role of vitamin D in mitochondrial health, cardiac function, and human reproduction

AM Reddy, M Iqbal, H Chopra, S Urmi, S Junapudi… - EXCLI …, 2022 - ncbi.nlm.nih.gov
Vitamin D, a secosteroid hormone, appears to have significant beneficial effects on various
physiological systems, including the musculoskeletal system. Vitamin D assists in the …

Sirtuin 1 and vascular function in healthy women and men: a randomized clinical trial comparing the effects of energy restriction and resveratrol

GHF Gonçalinho, KL Kuwabara, NFO Faria, MFS Goes… - Nutrients, 2023 - mdpi.com
Background: Sirtuin 1 (SIRT1) has been associated with longevity and protection against
cardiometabolic diseases, but little is known about how it influences human vascular …

Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway

X Liu, Y Xu, S Cheng, X Zhou, F Zhou, P He… - Frontiers in …, 2021 - frontiersin.org
Inflammation and apoptosis of vascular endothelial cells play a key role in the occurrence
and development of atherosclerosis (AS), and the AMPK/mTOR/Nrf2 signaling pathway …

Vulnerable atherosclerotic plaque: is there a molecular signature?

RM Chiorescu, M Mocan, AI Inceu, AP Buda… - International Journal of …, 2022 - mdpi.com
Atherosclerosis and its clinical manifestations, coronary and cerebral artery diseases, are
the most common cause of death worldwide. The main pathophysiological mechanism for …

The role of ferroptosis in cardiovascular disease and its therapeutic significance

Z Chen, Y Yan, C Qi, J Liu, L Li, J Wang - Frontiers in cardiovascular …, 2021 - frontiersin.org
Cardiovascular diseases (CVDs) are the leading cause of deaths worldwide with regulated
cell death playing an important role in cardiac pathophysiology. However, the classical …

The Effects of Porphyromonas gingivalis on Atherosclerosis-Related Cells

J Zhang, M Xie, X Huang, G Chen, Y Yin, X Lu… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis (AS), one of the most common types of cardiovascular disease, has initially
been attributed to the accumulation of fats and fibrous materials. However, more and more …

Diabetic retinopathy in patients with diabetic foot ulcer: A systematic review

D Serban, N Papanas, AM Dascalu… - … Journal of Lower …, 2021 - journals.sagepub.com
This review discusses the evidence on diabetic retinopathy (DR) in patients with diabetic
foot ulceration (DFU). A systematic literature review was performed on PubMed, Medline …