[HTML][HTML] Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions

YB Liu, MK Chen - World journal of gastroenterology, 2022 - ncbi.nlm.nih.gov
Cirrhosis causes a heavy global burden. In this review, we summarized up-to-date
epidemiological features of cirrhosis and its complications. Recent epidemiological studies …

Epidemiology and disease burden of alcohol associated liver disease

A Aslam, PY Kwo - Journal of Clinical and Experimental Hepatology, 2023 - Elsevier
Consumption of alcohol in excess leads to substantial medical, economic, and societal
burdens. Approximately 5.3% of all global deaths may be attributed to alcohol consumption …

STING mediates hepatocyte pyroptosis in liver fibrosis by epigenetically activating the NLRP3 inflammasome

Y Xiao, C Zhao, Y Tai, B Li, T Lan, E Lai, W Dai, Y Guo… - Redox Biology, 2023 - Elsevier
The activation of stimulator of interferon genes (STING) and NOD-like receptor protein 3
(NLRP3) inflammasome-mediated pyroptosis signaling pathways represent two distinct …

Mitochondria and the NLRP3 inflammasome in alcoholic and nonalcoholic steatohepatitis

S Torres, P Segalés, C García-Ruiz… - Cells, 2022 - mdpi.com
Alcoholic (ASH) and nonalcoholic steatohepatitis (NASH) are advanced stages of fatty liver
disease and two of the most prevalent forms of chronic liver disease. ASH and NASH are …

Prevalence, co‐morbidities, and in‐hospital mortality of patients hospitalized with alcohol‐associated hepatitis in the United States from 2015 to 2019

N Marlowe, D Lam, W Krebs, WQ Lin… - Alcoholism: Clinical …, 2022 - Wiley Online Library
Background The goals of our study are to determine the most recent trends in
hospitalization, mortality, and healthcare utilization among hospitalized patients with alcohol …

Telomere dysfunction in chronic liver disease: The link from aging

DD Penrice, N Jalan-Sakrikar, D Jurk, JF Passos… - Hepatology, 2024 - journals.lww.com
Aging can be defined as a functional decline in the physiological integrity of a living
organism over time. It can lead to disruption in homeostasis not only at the whole organism …

Pathogenesis of alcohol-associated fatty liver: lessons from transgenic mice

A Ferdouse, RD Clugston - Frontiers in physiology, 2022 - frontiersin.org
Alcohol-associated liver disease (ALD) is a major public health issue that significantly
contributes to human morbidity and mortality, with no FDA-approved therapeutic intervention …

Raman scattering-based optical sensing of chronic liver diseases

K Alkhuder - Photodiagnosis and Photodynamic Therapy, 2023 - Elsevier
Chronic liver diseases (CLDs) are a major public health problem. Despite the progress
achieved in fighting against viral hepatitis, the emergence of non-alcoholic fatty liver disease …

Epidemic within a pandemic: Alcohol‐associated hepatitis and COVID‐19

N Marlowe, D Lam… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background There was an increase in alcoholic beverage sales during the peak of the
COVID pandemic in the United States. However, little is known about the impact of SARS …

Non-invasive tests for alcohol-associated liver disease

M Israelsen, W Rungratanawanich, M Thiele… - Hepatology, 2024 - journals.lww.com
Alcohol consumption is a global phenomenon and a major contributor to alcohol-associated
liver disease (ALD). Detecting individuals at risk of ALD has been challenging, with only a …