Stable conjugates of peptides with gold nanorods for biomedical applications with reduced effects on cell viability

C Adura, S Guerrero, E Salas, L Medel… - … applied materials & …, 2013 - ACS Publications
Gold nanorods used in therapy and diagnosis must be nontoxic and stable in biological
media and should be specific for the target. The complete combination of these three factors …

Cellular delivery of RNA nanoparticles

L Parlea, A Puri, W Kasprzak, E Bindewald… - Therapeutic RNA …, 2021 - taylorfrancis.com
RNA nanostructures can be programmed to exhibit defined sizes, shapes and
stoichiometries from naturally occurring or de novo designed RNA motifs. These constructs …

First step of the cell‐penetrating peptide mechanism involves Rac1 GTPase‐dependent actin‐network remodelling

S Gerbal‐Chaloin, C Gondeau… - Biology of the …, 2007 - Wiley Online Library
Background information. Application of CPPs (cell‐penetrating peptides) constitutes a
promising strategy for the intracellular delivery of therapeutic molecules. The non‐covalent …

GFP-complementation assay to detect functional CPP and protein delivery into living cells

N Milech, BAC Longville, PT Cunningham… - Scientific reports, 2015 - nature.com
Efficient cargo uptake is essential for cell-penetrating peptide (CPP) therapeutics, which
deliver widely diverse cargoes by exploiting natural cell processes to penetrate the cell's …

Noncovalently associated cell-penetrating peptides for gene delivery applications

NA Alhakamy, AS Nigatu, CJ Berkland… - Therapeutic …, 2013 - Taylor & Francis
The use of various cell-penetrating peptides (CPPs) to deliver genetic material for gene
therapy applications has been a topic of interest for more than 20 years. The delivery of …

[HTML][HTML] Happy birthday cell penetrating peptides: already 20 years

R Brasseur, G Divita - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2010 - Elsevier
The recent discovery of new potent therapeutic molecules that do not reach the clinic due to
poor delivery and low bioavailability has made of delivery a keystone in therapeutic …

Using the peptide bp100 as a cell‐penetrating tool for the chemical engineering of actin filaments within living plant cells

K Eggenberger, C Mink, P Wadhwani, AS Ulrich… - …, 2011 - Wiley Online Library
The delivery of externally applied macromolecules or nanoparticles into living cells still
represents a critically limiting step before the full capabilities of chemical engineering can be …

[HTML][HTML] PEP and CADY-mediated delivery of fluorescent peptides and proteins into living cells

L Kurzawa, M Pellerano, MC Morris - Biochimica et Biophysica Acta (BBA) …, 2010 - Elsevier
Cell-penetrating peptides (CPPs) constitute a family of peptides with the characteristic ability
to cross biological membranes and deliver cargo into the intracellular milieu. Several CPPs …

Chitin nanomaterials and nanocomposites for tissue repair

P Morganti, G Morganti, MB Coltelli - Marine-derived biomaterials for tissue …, 2019 - Springer
Chitin nanomaterials and nanocomposites are being used more frequently in tissue repair
and skin rejuvenation. In fact, with the increase in age, the prevention of skin diseases …

[图书][B] Pharmaceutical formulation development of peptides and proteins

L Hovgaard, S Frokjaer, M van de Weert - 1999 - taylorfrancis.com
Pharmaceutical formulation of peptides and proteins has become an important part of
modern drug development. Many new drugs are based on peptide or protein recombinant …