Cell-penetrating peptides (CPPs) constitute a family of peptides whose unique characteristic
is their ability to insert into and cross biological membranes. Cell-penetrating peptide …

Cell-penetrating peptides (CPPs) have great potential to deliver bioactive agents into cells.
Although there have been many recent advances in CPP-related research, it is still important …

Over the past years, numerous promising new metalorganic lead structures have been
developed exhibiting highly active cytostatic properties. However, the efficiency of such …

According to their distinct biological functions, membrane-active peptides are generally
classified as antimicrobial (AMP), cell-penetrating (CPP), or fusion peptides (FP). The former …

One goal of nanotechnology is to prepare cellular nanoprobes for various biological
applications where conventional molecular probes fall short of long-term stability and …

Gene silencing mediated by double-stranded small interfering RNA (siRNA) has been
widely investigated as a potential therapeutic approach for a variety of diseases and …

Background and purpose: Protein transduction domains (PTDs), such as Tat, antennapedia
homeoprotein (Antp), Rev and VP22, have been extensively utilized for intracellular delivery …

Synthetic vaccines utilize viral signatures to trigger immune responses. Although the
immune responses raised against the biochemical signatures of viruses are well …

Cell-penetrating peptides (CPP) are short sequences of cationic amino-acids that show a
surprising ability to traverse lipid bilayers. CPP are considered to be some of the most …

Structure analysis of the cell-penetrating peptide transportan 10 (TP10) revealed an
exemplary range of different conformations in the membrane-bound state. The bipartite …