Effects of antirejection drugs on innate immune cells after kidney transplantation

G Zaza, J Leventhal, L Signorini, G Gambaro… - Frontiers in …, 2019 - frontiersin.org
Over the last decades, our understanding of adaptive immune responses to solid organ
transplantation increased considerably and allowed development of immunosuppressive …

Gut mycobiome in patients with chronic kidney disease was altered and associated with immunological profiles

J Hu, S Wei, Y Gu, Y Wang, Y Feng, J Sheng… - Frontiers in …, 2022 - frontiersin.org
Objectives Mounting evidence suggests that bacterial dysbiosis and immunity disorder are
associated with patients with chronic kidney disease (CKD), but the mycobiome is beginning …

Risk factors for urosepsis in chronic kidney disease patients with urinary tract infections

Z Dimitrijevic, G Paunovic, D Tasic, B Mitic, D Basic - Scientific Reports, 2021 - nature.com
Occurrence of urosepsis is not uncommon following urinary tract infections (UTI). However,
there is a lack of evidence explaining the risk factors predisposing to urosepsis in patients …

The emerging role of innate immunity in chronic kidney diseases

PCT Tang, YY Zhang, MKK Chan, WWY Lam… - International journal of …, 2020 - mdpi.com
Renal fibrosis is a common fate of chronic kidney diseases. Emerging studies suggest that
unsolved inflammation will progressively transit into tissue fibrosis that finally results in an …

TGF-β1 signaling: immune dynamics of chronic kidney diseases

PCT Tang, ASW Chan, CB Zhang… - Frontiers in …, 2021 - frontiersin.org
Chronic kidney disease (CKD) is a major cause of morbidity and mortality worldwide,
imposing a great burden on the healthcare system. Regrettably, effective CKD therapeutic …

The innate immune system and cardiovascular disease in ESKD: monocytes and natural killer cells

E Dounousi, A Duni, KK Naka… - Current Vascular …, 2021 - ingentaconnect.com
Adverse innate immune responses have been implicated in several disease processes,
including cardiovascular disease (CVD) and chronic kidney disease (CKD). The monocyte …

[HTML][HTML] Preexisting comorbidities shape the immune response associated with severe COVID-19

S Kreutmair, M Kauffmann, S Unger… - Journal of Allergy and …, 2022 - Elsevier
Background Comorbidities are risk factors for development of severe coronavirus disease
2019 (COVID-19). However, the extent to which an underlying comorbidity influences the …

Acute kidney injury associated to COVID-19 leads to a strong unbalance of circulant immune mediators

T Medeiros, GMC Guimarães, FR Carvalho, LS Alves… - Cytokine, 2022 - Elsevier
Background Severe cases of coronavirus disease 2019 (COVID-19) have increased risk for
acute kidney injury (AKI). The exacerbation of the immune response seems to contribute to …

Immunopathogenesis of acute kidney injury

ZA Radi - Toxicologic Pathology, 2018 - journals.sagepub.com
Pathophysiologically, the classification of acute kidney injury (AKI) can be divided into three
categories:(1) prerenal,(2) intrinsic, and (3) postrenal. Emerging evidence supports the …

Assessing and counteracting fibrosis is a cornerstone of the treatment of CKD secondary to systemic and renal limited autoimmune disorders

M de Cos, M Xipell, A García-Herrera, GM Lledo… - Autoimmunity …, 2022 - Elsevier
Chronic kidney disease (CKD) is an increasing cause of morbidity and mortality worldwide.
Besides the higher prevalence of diabetes, hypertension and aging worldwide, immune …