Acute kidney injury (AKI) has gained significant attention following patient safety alerts about
the increased risk of harm to patients, including increased mortality and hospitalization …

Artemisinin (ARS) and its derivatives (ARSs) are recommended as the first-line antimalarial
drugs for the treatment of malaria. Besides antimalarial function, its potent anti-inflammatory …

Background The difference between an individual's chronological and DNA methylation
predicted age (DNAmAge), termed DNAmAge acceleration (DNAmAA), can capture life-long …

Diabetic nephropathy (DN) is considered the main cause of kidney disease in which
myofibroblasts lead to renal fibrosis. Macrophages were recently identified as the major …

Background: Renal fibrosis is a key pathological change that occurs in the progression of
almost all chronic kidney diseases. CKD has the characteristics of high morbidity and …

Severe glomerular injury ultimately leads to tubulointerstitial fibrosis that determines patient
outcome, but the immunological molecules connecting these processes remain …

Chemical modifications are a specific and efficient way to regulate the function of biological
macromolecules. Among them, RNA molecules exhibit a variety of modifications that play …

Background: The glomerular endothelial glycocalyx is degraded during inflammation. The
glycocalyx plays a pivotal role in endothelial function and is involved in many processes …

Background: Low-grade inflammation is a significant component of chronic kidney disease
(CKD). Systemic immune inflammation index (SII), a newly defined ratio combining …

Machine preservation (MP) has emerged as a promising technology in liver transplantation,
but the cellular processes occurring during MP have not been characterized. Recent studies …