Hyaluronan, a double-edged sword in kidney diseases

A Kaul, KL Singampalli, UM Parikh, L Yu… - Pediatric …, 2022 - Springer
Over the years, hyaluronic acid (HA) has emerged as an important molecule in
nephrological and urological studies involving extracellular matrix (ECM) organization …

Neutrophil extracellular traps in the establishment and progression of renal diseases

H Salazar-Gonzalez, A Zepeda-Hernandez, Z Melo… - Medicina, 2019 - mdpi.com
Uncontrolled inflammatory and immune responses are often involved in the development of
acute and chronic forms of renal injury. Neutrophils are innate immune cells recruited early …

Immunology of Kidney Disease

O Foresto-Neto, L Menezes-Silva… - Annual Review of …, 2024 - annualreviews.org
The immune system and the kidneys are closely related. Immune components mediate
acute kidney disease and are crucial to the progression of chronic kidney disease. Beyond …

Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities

MC Stein, F Braun, CF Krebs, MJ Bunders - Cell and tissue research, 2021 - Springer
Acute and chronic kidney diseases are major contributors to morbidity and mortality in the
global population. Many nephropathies are considered to be immune-mediated with …

Curcumin and vitamin C improve immunity of kidney via gene expression against diethyl nitrosamine induced nephrotoxicity in rats: In vivo and molecular docking …

ABM Mehany, IM Farrag, M Diab, MM Ghoneim… - Heliyon, 2023 - cell.com
Kidney has a crucial role in immunity, so any toxicity occurs for the kidney will result in
reduced immunity. The aim of this study is to improve the immune response of insufficient …

Suppression of Indoxyl Sulfate Accumulation Reduces Renal Fibrosis in Sulfotransferase 1a1-Deficient Mice

H Hou, M Horikawa, Y Narita, H Jono… - International Journal of …, 2023 - mdpi.com
Renal fibrosis is the final manifestation of chronic kidney disease (CKD); its prevention is
vital for controlling CKD progression. Indoxyl sulfate (IS), a typical sulfate-conjugated uremic …

An inflammatory story: antibodies in tuberculosis comorbidities

MR McLean, LL Lu, SJ Kent, AW Chung - Frontiers in immunology, 2019 - frontiersin.org
Mycobacterium tuberculosis (Mtb) resides in a quarter of the world's population and is the
causative agent for tuberculosis (TB), the most common infectious reason of death in …

Therapeutic potential of annexin A1 modulation in kidney and cardiovascular disorders

MS Mozaffari - Cells, 2021 - mdpi.com
Renal and cardiovascular disorders are very prevalent and associated with significant
morbidity and mortality. Among diverse pathogenic mechanisms, the dysregulation of …

New insights into the immunity and podocyte in glomerular health and disease: from pathogenesis to therapy in proteinuric kidney disease

PXM Rangel, A Priyadarshini… - Integrative Medicine in …, 2021 - journals.lww.com
Evidence has been furnished that immune cells, and immune-podocytes interactions have
increasingly become the focus of proteinuric kidney diseases, which affect millions of …

Nanocarriers as a tool for the treatment of colorectal cancer

AL C. de SL Oliveira, T Schomann, LF de Geus-Oei… - Pharmaceutics, 2021 - mdpi.com
Nanotechnology is a promising tool for the treatment of cancer. In the past decades, major
steps have been made to bring nanotechnology into the clinic in the form of nanoparticle …