Anticancer potential of the S‐heterocyclic ring containing drugs and its bioactivation to reactive metabolites

S Maji, B Debnath, S Panda, T Manna… - Chemistry & …, 2024 - Wiley Online Library
Sulfur‐containing heterocyclic derivatives have been disclosed for binding with a wide
range of cancer‐specific protein targets. Various interesting derivatives of sulfur‐containing …

[HTML][HTML] Design and synthesis of new 4-(3, 4, 5-trimethoxyphenyl) thiazole–pyrimidine derivatives as potential antiproliferative agents

AK El-Damasy, H Jin, MA Sabry, HJ Kim, MM Alanazi… - Medicina, 2023 - mdpi.com
A new series of 3, 4, 5-trimethoxyphenyl thiazole pyrimidines has been synthesized and
biologically evaluated for its in vitro anticancer activity. Compounds 4a, 4b, and 4h with …

[HTML][HTML] Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae

WH Abdulaal, NA Alhakamy, AH Asseri… - Frontiers in …, 2024 - frontiersin.org
The development of resistance to carbapenems in Klebsiella pneumoniae due to the
production of metallo-β-lactamases (MBLs) is a critical public health problem because …

Investigation of the effects of thiazole compounds on thioredoxin reductase 1 (TrxR1), glutathione S‐transferase (GST), and glutathione reductase (GR) targeted …

IN Korkmaz - Biotechnology and Applied Biochemistry, 2024 - Wiley Online Library
Cancer is a fatal disease that kills thousands of people worldwide. Despite the information
produced by research on cancer treatment, applications in cancer treatment are limited …

Antibiofilm, cellular antioxidant, anti-inflammatory, immunomodulatory, cytotoxic, and antimutagenic activities of soluble melanins from Randia echinocarpa fruit

YP Ahumada-Santos, G López-Angulo… - Advances in Traditional …, 2024 - Springer
Melanins are widely distributed biopolymers that exhibit important biological activities.
However, fruit melanins have been scarcely studied. In this work, the antibiofilm, cellular …

Review; Recent approaches on Tubulin Polymerization inhibitors (2018-2022)

AO El-Abd - Delta University Scientific Journal, 2024 - journals.ekb.eg
Cancer is a disease in which some of the body's cells grow uncontrollably and spread to
other parts of the body. Cancer treatment usually involves the use of single or combined …

[PDF][PDF] Recent Review on 1, 3-Thiazole Derivatives as Therapeutic Targeted for Anticancer Activity

S Mishra, A Sahu - researchgate.net
In the past two decades, targeted cancer therapy has emerged as a novel class of
anticancer therapeutics besides traditional chemotherapy, surgery, and radiotherapy. There …