[HTML][HTML] D-Pinitol—active natural product from carob with notable insulin regulation

A Azab - Nutrients, 2022 - mdpi.com
Carob is one of the major food trees for peoples of the Mediterranean basin, but it has also
been traditionally used for medicinal purposes. Carob contains many nutrients and active …

[HTML][HTML] A systematic analysis of anti-diabetic medicinal plants from cells to clinical trials

S Omale, KI Amagon, TO Johnson, SK Bremner… - PeerJ, 2023 - peerj.com
Background Diabetes is one of the fastest-growing health emergencies of the 21 st century,
placing a severe economic burden on many countries. Current management approaches …

[HTML][HTML] Antiglycation, antioxidant, antiacne, and photoprotective activities of crude extracts and triterpene saponin fraction of Sapindus saponaria L. fruits: An in vitro …

RMG Silva, GR Martins, LMB Nucci… - Asian Pacific Journal …, 2022 - journals.lww.com
Objective: To evaluate the photoprotective, antioxidant, antiglycation, and antiacne activities
of crude extract (CESs) and triterpene saponin fraction (TSSs) of Sapindus saponaria …

[HTML][HTML] Avens root (Geum Urbanum L.) extract discovered by target-based screening exhibits antidiabetic activity in the Hen's egg test model and Drosophila …

I Günther, G Rimbach, S Nevermann… - Frontiers in …, 2021 - frontiersin.org
Medicinal plant extracts are becoming increasingly important as an alternative for traditional
drugs against diabetes mellitus (DM). For this reason, we initialized a target-based …

[HTML][HTML] Fluorescence microscopy-based quantitation of GLUT4 translocation

M Heckmann, G Klanert, G Sandner… - … and Applications in …, 2022 - iopscience.iop.org
Postprandial insulin-stimulated glucose uptake into target tissue is crucial for the
maintenance of normal blood glucose homeostasis. This step is rate-limited by the number …

[HTML][HTML] A Pilot Study on the Glucose-Lowering Effects of a Nutritional Supplement in People with Prediabetes

T Bemplidakis, I Eleftheriadou, O Kosta, K Tentolouris… - Diabetology, 2023 - mdpi.com
Background and Objectives: Prediabetes is associated with a high risk of developing
diabetes and cardiovascular disease. Early treatment with exercise and dietary interventions …

[PDF][PDF] A comprehensive in-vitro/in-vivo screening toolbox for the elucidation of glucose homeostasis modulating properties of plant extracts (from roots) and its …

I Bauer, G Rimbach, S Cordeiro… - Frontiers in …, 2024 - researchgate.net
Insufficient reduction of (postprandial) blood glucose levels is strongly associated with the
pathogenesis of obesity and chronic metabolic disorders such as type 2 diabetes mellitus …

[PDF][PDF] In-vitro antidiabetic activity of a Bistorta officinalis Delarbre root extract can not be confirmed in the in-vivo models hen's egg test and Drosophila melanogaster.

I Bauer, G Rimbach, S Nevermann… - Journal of Physiology …, 2023 - researchgate.net
The potential of plant bioactives for the prevention and therapy of diabetes is increasingly
being recognized. In the present study we investigated the antidiabetic properties of an …

[HTML][HTML] Lipoprotein Particles as Shuttles for Hydrophilic Cargo

F Weber, M Axmann, A Horner, B Schwarzinger… - Membranes, 2023 - mdpi.com
Lipoprotein particles (LPs) are excellent transporters and have been intensively studied in
cardiovascular diseases, especially regarding parameters such as their class distribution …

[PDF][PDF] D-Pinitol—Active Natural Product from Carob with Notable Insulin Regulation. Nutrients 2022, 14, 1453

A Azab - 2022 - researchgate.net
Carob is one of the major food trees for peoples of the Mediterranean basin, but it has also
been traditionally used for medicinal purposes. Carob contains many nutrients and active …