How the association between obesity and inflammation may lead to insulin resistance and cancer

MN Amin, MS Hussain, MS Sarwar… - Diabetes & Metabolic …, 2019 - Elsevier
Background and objectives Obesity is associated with metabolic dysfunction and over
nutrition. Increased body mass index and obesity are strongly amalgamated with changes in …

FKBP51 and the molecular chaperoning of metabolism

KB Smedlund, ER Sanchez, TD Hinds - Trends in Endocrinology & …, 2021 - cell.com
The molecular chaperone FK506-binding protein 51 (FKBP51) is gaining attention as a
meaningful biomarker of metabolic dysfunction. This review examines the emerging …

Reversibility of endothelial dysfunction in diabetes: role of polyphenols

N Suganya, E Bhakkiyalakshmi, DVL Sarada… - British Journal of …, 2016 - cambridge.org
The endothelium, a thin single sheet of endothelial cells, is a metabolically active layer that
coats the inner surface of blood vessels and acts as an interface between the circulating …

Skeletal muscle as a treatment target for older adults with diabetes mellitus: The importance of a multimodal intervention based on functional category

T Omura, A Araki - Geriatrics & Gerontology International, 2022 - Wiley Online Library
Although the lifespan of people with diabetes has increased in many countries, the age‐
related increase in comorbidities (sarcopenia, frailty and disabilities) and diabetic …

[HTML][HTML] Antidiabetic Actions of Ethanol Extract of Camellia Sinensis Leaf Ameliorates Insulin Secretion, Inhibits the DPP-IV Enzyme, Improves Glucose Tolerance …

P Ansari, JMA Hannan, ST Choudhury, SS Islam… - Medicines, 2022 - mdpi.com
Camellia sinensis (green tea) is used in traditional medicine to treat a wide range of
ailments. In the present study, the insulin-releasing and glucose-lowering effects of the …

[HTML][HTML] Insulin Secretory Actions of Ethanol Extract of Eucalyptus citriodora Leaf, including Plasma DPP-IV and GLP-1 Levels in High-Fat-Fed Rats, as Well as …

P Ansari, ST Choudhury, YHA Abdel-Wahab - Metabolites, 2022 - mdpi.com
Due to the numerous adverse effects of synthetic drugs, researchers are currently studying
traditional medicinal plants to find alternatives for diabetes treatment. Eucalyptus citriodora …

[HTML][HTML] Amelioration of metabolic syndrome-associated cognitive impairments in mice via a reduction in dietary fat content or infusion of non-diabetic plasma

LA Johnson, KL Zuloaga, TL Kugelman, KS Mader… - …, 2016 - thelancet.com
Obesity, metabolic syndrome (MetS) and type 2 diabetes (T2D) are associated with
decreased cognitive function. While weight loss and T2D remission result in improvements …

Insulinotropic and antidiabetic properties of Eucalyptus citriodora leaves and isolation of bioactive phytomolecules

P Ansari, PR Flatt, P Harriott… - Journal of Pharmacy …, 2021 - academic.oup.com
Objective The aim of this study was to delineate the mechanisms of action of the plant
Eucalyptus citriodora used traditionally for the treatment of type 2 diabetes. Methods Insulin …

[HTML][HTML] Methyl Syringate Stimulates Glucose Uptake by Inhibiting Protein Tyrosine Phosphatases Relevant to Insulin Resistance

D Ahn, J Kwon, S Song, J Lee, S Yoon, SJ Chung - Life, 2023 - mdpi.com
Several protein tyrosine phosphatases (PTPs), particularly PTPN1, PTPN2, PTPN6, PTPN9,
PTPN11, PTPRS, and DUSP9, are involved in insulin resistance. Therefore, these PTPs …

Insulin resistance: a new consequence of altered carotid body chemoreflex?

SV Conde, MJ Ribeiro, BF Melo… - The Journal of …, 2017 - Wiley Online Library
Metabolic diseases affect millions of individuals across the world and represent a group of
chronic diseases of very high prevalence and relatively low therapeutic success, making …