Relevance and regulation of cell density
GE Neurohr, A Amon - Trends in cell biology, 2020 - cell.com
Cell density shows very little variation within a given cell type. For example, in humans
variability in cell density among cells of a given cell type is 100 times smaller than variation …
variability in cell density among cells of a given cell type is 100 times smaller than variation …
[HTML][HTML] Diverse relations between ABC transporters and lipids: An overview
J Neumann, D Rose-Sperling, UA Hellmich - Biochimica et Biophysica Acta …, 2017 - Elsevier
It was first discovered in 1992 that P-glycoprotein (Pgp, ABCB1), an ATP binding cassette
(ABC) transporter, can transport phospholipids such as phosphatidylcholine,− ethanolamine …
(ABC) transporter, can transport phospholipids such as phosphatidylcholine,− ethanolamine …
The distribution of cellular turnover in the human body
We integrated ubiquity, mass and lifespan of all major cell types to achieve a comprehensive
quantitative description of cellular turnover. We found a total cellular mass turnover of 80±20 …
quantitative description of cellular turnover. We found a total cellular mass turnover of 80±20 …
Metabolic regulation of species-specific developmental rates
M Diaz-Cuadros, TP Miettinen, OS Skinner, D Sheedy… - Nature, 2023 - nature.com
Animals display substantial inter-species variation in the rate of embryonic development
despite a broad conservation of the overall sequence of developmental events. Differences …
despite a broad conservation of the overall sequence of developmental events. Differences …
Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions
Glucose is vital for life, serving as both a source of energy and carbon building block for
growth. When glucose is limiting, alternative nutrients must be harnessed. To identify …
growth. When glucose is limiting, alternative nutrients must be harnessed. To identify …
Robust surface-to-mass coupling and turgor-dependent cell width determine bacterial dry-mass density
ER Oldewurtel, Y Kitahara… - Proceedings of the …, 2021 - National Acad Sciences
During growth, cells must expand their cell volumes in coordination with biomass to control
the level of cytoplasmic macromolecular crowding. Dry-mass density, the average ratio of …
the level of cytoplasmic macromolecular crowding. Dry-mass density, the average ratio of …
Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation
Metabolic regulation influences cell proliferation. The influence of pyruvate kinase isoforms
on tumor cells has been extensively studied, but whether PKM2 is required for normal cell …
on tumor cells has been extensively studied, but whether PKM2 is required for normal cell …
High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays
Methods to rapidly assess cell growth would be useful for many applications, including drug
susceptibility testing, but current technologies have limited sensitivity or throughput. Here we …
susceptibility testing, but current technologies have limited sensitivity or throughput. Here we …
A systematic evaluation of methods for tailoring genome-scale metabolic models
Genome-scale models of metabolism can illuminate the molecular basis of cell phenotypes.
Since some enzymes are only active in specific cell types, several algorithms use omics data …
Since some enzymes are only active in specific cell types, several algorithms use omics data …
Physiological basis for atmospheric methane oxidation and methanotrophic growth on air
T Schmider, AG Hestnes, J Brzykcy, H Schmidt… - Nature …, 2024 - nature.com
Atmospheric methane oxidizing bacteria (atmMOB) constitute the sole biological sink for
atmospheric methane. Still, the physiological basis allowing atmMOB to grow on air is not …
atmospheric methane. Still, the physiological basis allowing atmMOB to grow on air is not …