Clinical thrombophilia is the consequence of multiple gene and/or environment interactions.
Thrombophilia screening requires a targeted patient with specific indication, in which a …

Inherited thrombophilia is a blood coagulation disorder that increases the risk for venous
thromboembolism (VTE). During the last decades, the practice of testing has evolved from …

Before medical tests are introduced into practice, they should be properly evaluated.
Randomized trials and other comprehensive evaluations of tests and test strategies can best …

Thrombophilia is a well‐established risk factor for a venous thromboembolic event (VTE),
and it has been proposed that hereditary thrombophilia may substantially contribute to the …

Objective/Background The aim of this study was to estimate the lifetime cost-effectiveness of
endovascular aneurysm repair (EVAR) versus open surgical repair (OSR) in the …

BACKGROUND Thromboprophylaxis can reduce the risk of venous thromboembolism (VTE)
during lower-limb immobilisation, but it is unclear whether or not this translates into …

In this issue of Blood, Lijfering and colleagues provide data on the absolute risk for both
initial and recurrent venous thromboses in persons with thrombophilia. Based on these data …

Background. Evaluation of personalized treatment options requires health economic models
that include multiple patient characteristics. Patient-level discrete-event simulation (DES) …

A previous venous thromboembolism is the most important risk factor for predicting
recurrence of the condition. Several studies have shown that routine testing for inherited …

BACKGROUND Clinical guidelines recommend against routine use of thrombophilia testing
in patients with acute thromboembolism. Thrombophilia testing rarely changes acute …