LncRNA H19 promotes tumor angiogenesis in smokers by targeting anti-angiogenic miRNAs

M Shirvaliloo - Epigenomics, 2023 - Taylor & Francis
A key concept in drug discovery is the identification of candidate therapeutic targets such as
long noncoding RNAs (lncRNAs) because of their extensive involvement in neoplasms, and …

MicroRNAs in hypertrophic, arrhythmogenic and dilated cardiomyopathy

E Chiti, M Di Paolo, E Turillazzi, A Rocchi - Diagnostics, 2021 - mdpi.com
MicroRNAs (miRNAs) are a class of non-coding RNAs of about 20 nucleotides in length,
involved in the regulation of many biochemical pathways in the human body. The level of …

Biomarkers in acute myocarditis and chronic inflammatory cardiomyopathy: an updated review of the literature

G Crisci, E Bobbio, P Gentile, DI Bromage… - Journal of Clinical …, 2023 - mdpi.com
Myocarditis is a disease caused by cardiac inflammation that can progress to dilated
cardiomyopathy, heart failure, and eventually death. Several etiologies, including …

A systematic review of miRNA and cfDNA as potential biomarkers for liquid biopsy in myocarditis and inflammatory dilated cardiomyopathy

P Lewandowski, M Goławski, M Baron… - Biomolecules, 2022 - mdpi.com
Myocarditis and inflammatory dilated cardiomyopathy are cardiac diseases leading to heart
failure. Liquid biopsy is a concept of replacing traditional biopsy with specialized blood tests …

MicroRNAs: diagnostic, prognostic and therapeutic role in heart failure—a review

P Gargiulo, F Marzano, M Salvatore, C Basile… - ESC Heart …, 2023 - Wiley Online Library
Heart failure is a leading cause of morbidity and mortality, with relevant social and economic
burden on global healthcare system. Although the development of novel diagnostic tools …

Circulating cardiac MicroRNAs safeguard against dilated cardiomyopathy

X Cheng, D Jian, J Xing, C Liu, Y Liu… - Clinical and …, 2023 - Wiley Online Library
Background Cardiac‐resident or‐enriched microRNAs (miRNAs) could be released into the
bloodstream becoming circulating cardiac miRNAs, which are increasingly recognized as …

The role of MicroRNAs in dilated cardiomyopathy: new insights for an old entity

E Alonso-Villa, F Bonet, F Hernandez-Torres… - International Journal of …, 2022 - mdpi.com
Dilated cardiomyopathy (DCM) is a clinical diagnosis characterized by left ventricular or
biventricular dilation and systolic dysfunction. In most cases, DCM is progressive, leading to …

miRNA‐103‐3p‐Hlf regulates apoptosis and autophagy by targeting hepatic leukaemia factor in heart failure

P Xue, Y Liu, H Wang, J Huang, M Luo - ESC Heart Failure, 2023 - Wiley Online Library
Aims Cardiomyocyte apoptosis is an important factor leading to the occurrence and
development of heart failure (HF), which is associated with high mortality of patients with …

miRNAs in Heart Development and Disease

E Lozano-Velasco, JM Inácio, I Sousa… - International Journal of …, 2024 - mdpi.com
Cardiovascular diseases (CVD) are a group of disorders that affect the heart and blood
vessels. They include conditions such as myocardial infarction, coronary artery disease …

Robust rank aggregation and least absolute shrinkage and selection operator analysis of novel gene signatures in dilated cardiomyopathy

X Ma, C Mo, L Huang, P Cao, L Shen… - Frontiers in …, 2021 - frontiersin.org
Objective: Dilated cardiomyopathy (DCM) is a heart disease with high mortality
characterized by progressive cardiac dilation and myocardial contractility reduction. The …