Mental illness modeling is still a major challenge for scientists. Animal models of
schizophrenia are essential to gain a better understanding of the disease etiopathology and …

Background & Objective: A number of neuropsychiatric disorders, including Parkinson's
disease, schizophrenia, attention deficit hyperactivity disorder, and, to some extent …

Schizophrenia is a highly heritable, chronic, severe, disabling neurodevelopmental brain
disorder with a heterogeneous genetic and neurobiological background, which is still poorly …

Schizophrenia is a debilitating psychiatric disorder with a substantial socioeconomic and
humanistic burden. Currently available treatment strategies mostly rely on antipsychotic …

Schizophrenia (SCZ) is a severe neurodevelopmental disorder affecting 1% of populations
worldwide with a grave disability and socioeconomic burden. Current antipsychotic …

Antipsychotics are accompanied by extrapyramidal side effects that deter treatment
adherence and patient compliance. Paliperidone (PPD), an atypical (second-generation) …

It is now well accepted that psychostimulants act on glial cells causing neuroinflammation
and adding to the neurotoxic effects of such substances. Neuroinflammation can be …

Neuroinflammation has been implicated in the neurobiological pathways of schizophrenia.
This meta-analysis evaluated the efficacy and tolerability of adjunctive celecoxib as a …

The gut-brain axis is a multimodal communication system along which immune, metabolic,
autonomic, endocrine and enteric nervous signals can shape host physiology and …

Schizophrenia is a devastating psychiatric disorder with complex symptoms and
neurobiology. Serotonergic dysregulation is known to contribute to the pathogenesis of …