Peripheral T cell lymphomas: from the bench to the clinic

D Fiore, LV Cappelli, A Broccoli, PL Zinzani… - Nature Reviews …, 2020 - nature.com
Peripheral T cell lymphomas (PTCLs) are a heterogeneous group of orphan neoplasms.
Despite the introduction of anthracycline-based chemotherapy protocols, with or without …

Human endogenous retrovirus-K (HML-2): a comprehensive review

M Garcia-Montojo, T Doucet-O'Hare… - Critical reviews in …, 2018 - Taylor & Francis
The human genome contains a large number of retroviral elements acquired over the
process of evolution, some of which are specific to primates. However, as many of these are …

Viral oncology: molecular biology and pathogenesis

UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

Non-coding RNAs as mediators of epigenetic changes in malignancies

S Kumar, EA Gonzalez, P Rameshwar, JP Etchegaray - Cancers, 2020 - mdpi.com
Simple Summary This review discusses the role of non-coding RNAs (ncRNAs) in cancer
epigenetics, mostly focusing on how deregulated microRNAs (miRNAs) and long non …

The versatile role of exosomes in human retroviral infections: from immunopathogenesis to clinical application

J Rezaie, C Aslan, M Ahmadi, NM Zolbanin… - Cell & Bioscience, 2021 - Springer
Eukaryotic cells produce extracellular vesicles (EVs) mediating intercellular communication.
These vesicles encompass many bio-molecules such as proteins, nucleic acids, and lipids …

Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma

M Yamagishi, M Kubokawa, Y Kuze, A Suzuki… - Nature …, 2021 - nature.com
Subclonal genetic heterogeneity and their diverse gene expression impose serious
problems in understanding the behavior of cancers and contemplating therapeutic …

[HTML][HTML] HTLV-1 infection: An emerging risk. Pathogenesis, epidemiology, diagnosis and associated diseases

E Eusebio-Ponce, E Anguita… - Revista Española de …, 2019 - ncbi.nlm.nih.gov
ABSTRACT The Human T-Lymphotropic Virus type 1 (HTLV-1) affects up to 10 million
people worldwide. It is directly associated to one of the most aggressive T cell malignancies …

Human T cell leukemia virus type 1: persistence and pathogenesis

CRM Bangham - Annual review of immunology, 2018 - annualreviews.org
Human T cell leukemia virus type 1 (HTLV-1), also known as human T lymphotropic virus
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related …

HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

Human retroviral antisense mRNAs are retained in the nuclei of infected cells for viral persistence

G Ma, J Yasunaga, K Shimura… - Proceedings of the …, 2021 - National Acad Sciences
Human retroviruses, including human T cell leukemia virus type 1 (HTLV-1) and HIV type 1
(HIV-1), encode an antisense gene in the negative strand of the provirus. Besides coding for …