[HTML][HTML] Biocatalysis

EL Bell, W Finnigan, SP France, AP Green… - Nature Reviews …, 2021 - nature.com
Biocatalysis has become an important aspect of modern organic synthesis, both in
academia and across the chemical and pharmaceutical industries. Its success has been …

The living interface between synthetic biology and biomaterial design

AP Liu, EA Appel, PD Ashby, BM Baker, E Franco… - Nature materials, 2022 - nature.com
Recent far-reaching advances in synthetic biology have yielded exciting tools for the
creation of new materials. Conversely, advances in the fundamental understanding of soft …

Upcycling CO2 into energy-rich long-chain compounds via electrochemical and metabolic engineering

T Zheng, M Zhang, L Wu, S Guo, X Liu, J Zhao… - Nature Catalysis, 2022 - nature.com
Upcycling of carbon dioxide (CO2) into value-added products represents a substantially
untapped opportunity to tackle environmental issues and achieve a circular economy …

Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale

FE Liew, R Nogle, T Abdalla, BJ Rasor, C Canter… - Nature …, 2022 - nature.com
Many industrial chemicals that are produced from fossil resources could be manufactured
more sustainably through fermentation. Here we describe the development of a carbon …

Identification of bioactive metabolites using activity metabolomics

MM Rinschen, J Ivanisevic, M Giera… - Nature reviews Molecular …, 2019 - nature.com
The metabolome, the collection of small-molecule chemical entities involved in metabolism,
has traditionally been studied with the aim of identifying biomarkers in the diagnosis and …

Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris

P Cai, X Wu, J Deng, L Gao, Y Shen… - Proceedings of the …, 2022 - National Acad Sciences
Methanol-based biorefinery is a promising strategy to achieve carbon neutrality goals by
linking CO2 capture and solar energy storage. As a typical methylotroph, Pichia pastoris …

Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol

J Gao, Y Li, W Yu, YJ Zhou - Nature Metabolism, 2022 - nature.com
Methanol is an ideal feedstock for biomanufacturing that can be beneficial for global carbon
neutrality; however, the toxicity of methanol limits the efficiency of methanol metabolism …

Common principles and best practices for engineering microbiomes

CE Lawson, WR Harcombe, R Hatzenpichler… - Nature Reviews …, 2019 - nature.com
Despite broad scientific interest in harnessing the power of Earth's microbiomes, knowledge
gaps hinder their efficient use for addressing urgent societal and environmental challenges …

Tools and strategies of systems metabolic engineering for the development of microbial cell factories for chemical production

YS Ko, JW Kim, JA Lee, T Han, GB Kim… - Chemical Society …, 2020 - pubs.rsc.org
Sustainable production of chemicals from renewable non-food biomass has become a
promising alternative to overcome environmental issues caused by our heavy dependence …

Role of biocatalysis in sustainable chemistry

RA Sheldon, JM Woodley - Chemical reviews, 2018 - ACS Publications
Based on the principles and metrics of green chemistry and sustainable development,
biocatalysis is both a green and sustainable technology. This is largely a result of the …