The first report demonstrating that prolonged endurance exercise promotes oxidative stress
in humans was published more than 4 decades ago. Since this discovery, many ensuing …

The first suggestion that physical exercise results in free radical-mediated damage to tissues
appeared in 1978, and the past three decades have resulted in a large growth of knowledge …

This review concentrates on advances in nitric oxide synthase (NOS) structure, function and
inhibition made in the last seven years, during which time substantial advances have been …

Mitochondria are a quantitatively relevant source of reactive oxygen species (ROS) in the
majority of cell types. Here we review the sources and metabolism of ROS in this organelle …

It is well established that contracting muscles produce both reactive oxygen and nitrogen
species. Although the sources of oxidant production during exercise continue to be debated …

In the past five years, skeletal muscle has emerged as a paradigm of “nitric oxide”(NO)
function and redox-related signaling in biology. All major nitric oxide synthase (NOS) …

Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

Nitric oxide (NO) is synthesized from l-arginine by NO synthase in virtually all cell types.
Emerging evidence shows that NO regulates the metabolism of glucose, fatty acids and …

Varicocele is recognized as the leading cause of male infertility because it can impair
spermatogenesis through several distinct pathophysiological mechanisms. Current …

The physiological role of nitric oxide (NO) in the maintenance of vascular tone, in synaptic
transmission and in cellular defence is now firmly established. Recent evidence indicates …