Abstract mRNA-Lipid nanoparticles (LNPs) are at the forefront of global medical research.
With the development of mRNA-LNP vaccines to combat the COVID-19 pandemic, the …

The development of therapeutic approaches for the induction of robust, long-lasting and
antigen-specific immune tolerance remains an important unmet clinical need for the …

Abstract Atezolizumab (anti-PD-L1) combined with bevacizumab (anti-VEGFA) is the first-
line immunotherapy for advanced hepatocellular carcinoma (HCC), but the number of …

Dendritic cells (DCs) are myeloid cells bridging the innate and adaptive immune system. By
cross‐presenting tumor‐associated antigens (TAAs) liberated upon spontaneous or therapy …

Conventional dendritic cells (DCs) are essential mediators of antitumor immunity. As a
result, cancers have developed poorly understood mechanisms to render DCs dysfunctional …

The efficient activation of professional antigen‐presenting cells—such as dendritic cells
(DC)—in tumors and lymph nodes is critical for the design of next‐generation cancer …

Immune cells experience large cell shape changes during environmental patrolling because
of the physical constraints that they encounter while migrating through tissues. These cells …

Purpose: Radiation-mediated immune suppression limits efficacy and is a barrier in cancer
therapy. Radiation induces negative regulators of tumor immunity including regulatory T …

Checkpoint inhibitors, specifically anti–PD-1, have shown success in treating metastatic
melanoma; however, some patients develop resistance. Dendritic cells (DCs) play a key role …

Background Ascaris lumbricoides cystatin (Al-CPI) prevents the development of allergic
airway inflammation and dextran-induced colitis in mice models. It has been suggested that …