Recently, a strong correlation between metabolic disorders, tumor onset, and progression
has been demonstrated, directing new therapeutic strategies on metabolic targets. OLR1 …

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Despite
significant progress that has been made in therapies against CRC over the past decades …

Background & Aims Because inflammatory bowel disease is increasing worldwide and can
lead to colitis-associated carcinoma (CAC), new interventions are needed. We have shown …

Histopathological image analysis is the gold standard for pathologists to grade colorectal
cancers of different differentiation types. However, the diagnosis by pathologists is highly …

Background: Previous studies on the systemic immune-inflammation index (SII), which is
based on platelet, neutrophil and lymphocyte counts, as a prognostic marker in patients with …

Colorectal cancer (CRC) is a gastrointestinal malignancy originating from either the colon or
the rectum. A growing number of researches prove that the unfolded protein response (UPR) …

Colorectal cancer (CRC) is a usual digestive tract malignancy and the third main cause of
cancer death around the world, with a high occurrence rate and mortality rate. Conventional …

Alkaloids derived from natural products have been traditionally used to treat various
diseases, including cancers. Rutaecarpine (1), a β-carboline-type alkaloid obtained from …

Oral administration is the preferred route of administration based on the convenience for and
compliance of the patient. Oral nanomedicines have been developed to overcome the …

Colorectal cancer (CRC) is a common malignant tumor with a high frequency of recurrence
and metastasis, which are the major causes of death in patients. The prerequisite for the …