Alzheimer's disease (AD) and epilepsy are common neurological disorders in the elderly. A
bi-directional link between these neurological diseases has been reported, with patients …

In children and adolescents with epilepsy, neurodevelopmental comorbidities can impair the
quality of life more than seizures. The aim of this review was to evaluate the cognitive and …

Genetic factors contribute to the aetiology of epilepsy in> 50% of cases, and information on
the use of antiseizure medications in people with specific aetiologies will help guide …

Perampanel (PER) is a new type of antiseizure medication used for partial or generalized
seizures. However, the plasma concentration shows obvious individual variability in …

Introduction Drug management of epilepsy in the elderly presents unique but data on this
population are scarce. This study aimed to assess the effectiveness and tolerability of …

Previously, we demonstrated that palmatine (PALM)–an isoquinoline alkaloid from Berberis
sibrica radix, exerted antiseizure activity in the pentylenetetrazole (PTZ)-induced seizure …

Autism spectrum disorders represent a diverse etiological spectrum that converge on a
syndrome characterized by discrepant deficits in developmental domains often highlighted …

In the landscape of paediatric epilepsy treatment, over 20 anti-seizure medications (ASMs)
have gained approval from Drug Regulatory Agencies, each delineating clear indications …

The quest for effective epilepsy treatments has spotlighted natural alkaloids due to their
broad neuropharmacological effects. This review provides a comprehensive analysis of the …

Spinal cord injury (SCI) afflicts millions of individuals globally. There are few therapies
available to patients. Ascending and descending excitatory glutamatergic neural circuits in …