Leukemia Inhibitory Factor (LIF) is a member of the IL-6 cytokine family and is expressed in
almost every tissue type within the body. Although LIF was named for its ability to induce …

Stroke is a leading cause of mortality and long-term disability worldwide, with limited
spontaneous repair processes occurring after injury. Immune cells are involved in multiple …

Inflammatory protein biomarkers induced by immune responses have been associated with
cognitive decline and the pathogenesis of Alzheimer's disease (AD). Here, we investigate …

Increasing evidence has challenged the traditional view about the immune privilege of the
brain, but the precise roles of immune cells in regulating brain physiology and function …

Potentially neurotoxic systems involved in traumatic and degenerative diseases of the brain
were assessed in acute psychosis. Astrocyte-derived exosomes (ADEs) and neuron-derived …

Background: Neuroinflammatory processes are common in neurodegenerative diseases
such as Alzheimer's disease (AD) and frontotemporal dementia (FTD), but current …

Abstract Sphingosine 1‐phosphate (S1P) is an essential lipid metabolite that signals
through a family of five G protein‐coupled receptors, S1PR1‐S1PR5, to regulate cell …

Bacterial Kidney Disease (BKD), which is caused by a Gram-positive, intracellular bacterial
pathogen (Renibacterium salmoninarum), affects salmonids including Atlantic salmon …

Encephalopathy of prematurity (EoP) is a major cause of morbidity in preterm neonates,
causing neurodevelopmental adversities that can lead to lifelong impairments. Preterm birth …

A limited number of peripheral targets generate pain. Inflammatory mediators can sensitize
these. The review addresses targets acting exclusively or predominantly on sensory …