Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of
action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors …

NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic eosinophilic, inflammatory
disorder of the respiratory tract occurring in patients with asthma and/or chronic …

Background Aspirin-exacerbated respiratory disease (AERD) is manifested by adult-onset
asthma, nasal polyposis, chronic rhinosinusitis, and aspirin sensitivity. Previously reported …

Hypersensitivity reactions to aspirin (acetylsalicylic acid) and other nonsteroidal anti‐
inflammatory drugs (NSAID s) constitute only a subset of all adverse reactions to these …

When questioned, about 10% of the parents report suspected hypersensitivity to at least one
drug in their children. However, only a few of these reactions can be confirmed as allergic …

Objectives This review attempts to bring together information from a large number of recent
studies on the clinical uses, safety and pharmacological properties of ibuprofen. Ibuprofen is …

To cite this article: Kowalski ML, Makowska JS, Blanca M, Bavbek S, Bochenek G, Bousquet
J, Bousquet P, Celik G, Demoly P, Gomes ER, Niżankowska‐Mogilnicka E, Romano A …

Paracetamol (acetaminophen) is generally considered to be a weak inhibitor of the
synthesis of prostaglandins (PGs). However, the in vivo effects of paracetamol are similar to …

For more than three decades, acetaminophen (INN, paracetamol) has been claimed to be
devoid of significant inhibition of peripheral prostanoids. Meanwhile, attempts to explain its …