[HTML][HTML] Hyaluronan-estradiol nanogels as potential drug carriers to target ER+ breast cancer cell line

L Paoletti, N Zoratto, M Benvenuto, D Nardozi… - Carbohydrate …, 2023 - Elsevier
An innovative hyaluronan-based nano-delivery system is proposed for the active targeting
towards ER+ breast cancer. Hyaluronic acid (HA), an endogenous and bioactive anionic …

Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo

M Benvenuto, V Angiolini, C Focaccetti, D Nardozi… - Biology Direct, 2023 - Springer
Background Malignant mesothelioma (MM) is a rare tumor with a dismal prognosis. The low
efficacy of current treatment options highlights the urge to identify more effective therapies …

Curcumin potentiates the ErbB receptors inhibitor Afatinib for enhanced antitumor activity in malignant mesothelioma

M Benvenuto, D Nardozi, C Palumbo… - … Journal of Food …, 2023 - Taylor & Francis
Several attempts have been made to develop targeted therapies for malignant
mesothelioma (MM), an aggressive tumour with a poor prognosis. In this study we evaluated …

Dauricine attenuates Oct4/sonic hedgehog co‐activated stemness and induces reactive oxygen species‐mediated mitochondrial apoptosis via AKT/β‐catenin …

C Liu, T Yang, C Cheng, J Huo, X Peng… - Phytotherapy …, 2024 - Wiley Online Library
Neuroblastoma and glioblastoma are primary malignant tumors of the nervous system, with
frequent relapse and limited clinical therapeutic drugs. The failure of their treatment is due to …

Bisphenol-A in Drinking Water Accelerates Mammary Cancerogenesis and Favors an Immunosuppressive Tumor Microenvironment in BALB–neuT Mice

C Focaccetti, D Nardozi, M Benvenuto… - International Journal of …, 2024 - mdpi.com
Bisphenol-A (BPA), a synthetic compound ubiquitously present in the environment, can act
as an endocrine disruptor by binding to both canonical and non-canonical estrogen …

Mesotelioma pleuroperitoneal maligno infantil con alta supervivencia

IC Aguirrechu, LC Fernández… - Revista Cubana de …, 2024 - revpediatria.sld.cu
Introducción: El mesotelioma maligno es un tipo de tumor poco frecuente, en particular en la
infancia. Alrededor del 80% son pleurales o peritoneales y tiene pobre respuesta al …