Rheumatoid arthritis is a heterogeneous disease, which can be, based on data combining
genetic risk factors and autoantibodies, sub-classified into ACPA-positive and-negative RA …

Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …

We elucidated the molecular cross-talk between cartilage and synovium in osteoarthritis, the
most widespread arthritis in the world, using the powerful tool of single-cell RNA …

The molecular mechanisms of osteoarthritis, the most common chronic disease, remain
unexplained. This study aimed to use bioinformatic methods to identify the key biomarkers …

Background Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder
characterized by inflammatory cell infiltration, leading to persistent synovitis and joint …

Tissue macrophages (Mϕ) are essential effector cells in rheumatoid arthritis (RA),
contributing to autoimmune tissue inflammation through diverse effector functions. Their …

The synovium is the major target tissue of inflammatory arthritides such as rheumatoid
arthritis. The study of synovial tissue has advanced considerably throughout the past few …

Rheumatoid arthritis is a systemic autoimmune disease, but disease flares typically affect
only a subset of joints, distributed in a distinctive pattern for each patient. Pursuing this …

Rheumatoid arthritis is a chronic autoimmune disease characterized by persistent
hyperplasia of the synovial membrane and progressive erosion of articular cartilage …

Abstract Purpose of Review The purpose of this review is to explore the role of monocyte
chemoattractant protein-1 (MCP-1 or CCL2) in the processes that underpin bone …