From genome to drugs: new approaches in antimicrobial discovery
F Serral, FA Castello, EJ Sosa, AM Pardo… - Frontiers in …, 2021 - frontiersin.org
Decades of successful use of antibiotics is currently challenged by the emergence of
increasingly resistant bacterial strains. Novel drugs are urgently required but, in a scenario …
increasingly resistant bacterial strains. Novel drugs are urgently required but, in a scenario …
A journey through the Corynebacterium pseudotuberculosis proteome promotes insights into its functional genome
Background Corynebacterium pseudotuberculosis is a Gram-positive facultative intracellular
pathogen and the etiologic agent of illnesses like caseous lymphadenitis in small ruminants …
pathogen and the etiologic agent of illnesses like caseous lymphadenitis in small ruminants …
An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets
PIP Ramos, D Fernández Do Porto, E Lanzarotti… - Scientific reports, 2018 - nature.com
Klebsiella pneumoniae (Kp) is a globally disseminated opportunistic pathogen that can
cause life-threatening infections. It has been found as the culprit of many infection outbreaks …
cause life-threatening infections. It has been found as the culprit of many infection outbreaks …
[HTML][HTML] Prediction of new vaccine targets in the core genome of Corynebacterium pseudotuberculosis through omics approaches and reverse vaccinology
CL Araújo, J Alves, W Nogueira, LC Pereira… - Gene, 2019 - Elsevier
Corynebacterium pseudotuberculosis is the etiologic agent of veterinary relevance
diseases, such as caseous lymphadenitis, affecting different animal species causing …
diseases, such as caseous lymphadenitis, affecting different animal species causing …
PBIT: pipeline builder for identification of drug targets for infectious diseases
G Shende, H Haldankar, RS Barai, MH Bharmal… - …, 2017 - academic.oup.com
Abstract Summary PBIT (Pipeline Builder for Identification of drug Targets) is an online
webserver that has been developed for screening of microbial proteomes for critical features …
webserver that has been developed for screening of microbial proteomes for critical features …
Exploring and targeting potential druggable antimicrobial resistance targets ArgS, SecY, and MurA in Staphylococcus sciuri with TCM inhibitors through a subtractive …
A Khan, S Sohail, S Yaseen, S Fatima, A Wisal… - Functional & Integrative …, 2023 - Springer
Staphylococcus sciuri (also currently Mammaliicoccus sciuri) are anaerobic facultative and
non-motile bacteria that cause significant human pathogenesis such as endocarditis, wound …
non-motile bacteria that cause significant human pathogenesis such as endocarditis, wound …
Subtractive sequence analysis aided druggable targets mining in Burkholderia cepacia complex and finding inhibitors through bioinformatics approach
Burkholderia cepacia complex (BCC) is a group of gram-negative bacteria composed of at
least 20 different species that cause diseases in plants, animals as well as humans (cystic …
least 20 different species that cause diseases in plants, animals as well as humans (cystic …
Recombinant esterase from Corynebacterium pseudotuberculosis in DNA and subunit recombinant vaccines partially protects mice against challenge
AA Brum, AFS Rezende… - Journal of medical …, 2017 - microbiologyresearch.org
Purpose. We tested the efficacy of the esterase encoded by cp1002_RS09720 from
Corynebacterium pseudotuberculosis in recombinant subunit and DNA caseous …
Corynebacterium pseudotuberculosis in recombinant subunit and DNA caseous …
Delineating Novel Therapeutic Drug and Vaccine Targets for Staphylococcus cornubiensis NW1T Through Computational Analysis
Staphylococcal multidrug resistance is an emerging future threat. Among staphylococci
species, Staphylococcus intermedius group (SIG) comprises of coagulase-positive four …
species, Staphylococcus intermedius group (SIG) comprises of coagulase-positive four …
The Druggable Pocketome of Corynebacterium diphtheriae: A New Approach for in silico Putative Druggable Targets
Diphtheria is an acute and highly infectious disease, previously regarded as endemic in
nature but vaccine-preventable, is caused by Corynebacterium diphtheriae (Cd). In this …
nature but vaccine-preventable, is caused by Corynebacterium diphtheriae (Cd). In this …