Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

Abstract The High-Mobility Group Box-1 (HMGB1), a non-histone chromatin-associated
protein, plays a crucial role in cancer growth and response to therapy as it retains a pivotal …

Regional lymph node metastasis is an important predictor for survival outcome and an
indicator for postoperative adjuvant chemotherapy in patients with colorectal cancer. Even …

High-mobility group box 1 (HMGB1), a member of damage-associated molecular patterns
(DAMPs), is involved in the immune regulation of several infectious diseases. Mycoplasma …

Post-translational modifications (PTMs) of the non-histone protein high-mobility group
protein B1 (HMGB1) are involved in modulating inflammation and immune responses …

Background Novel strategies are required since the hypoxic tumor microenvironment is one
of the important impediments for conventional cancer therapy. High mobility group box 1 …

Few reports exist regarding the expression and function of Wilms' tumor 1-associated protein
(WTAP) in colorectal cancer (CRC), and the evidence is controversial. Our analysis explored …

Tumor multidrug resistance (MDR) remains one of the most challenging barriers to
successful cancer treatment. Several previous studies have suggested that high mobility …

Simple Summary New treatment targets are urgently needed for colorectal cancer. Here, we
investigate the role of HMGB1—a multifunctional immune protein—in colorectal cancer. We …

Background Deregulation of cell death is a common characteristic of cancer, and resistance
to this process often occurs in lung cancer. Understanding the molecular mechanisms …