The immune contexture and Immunoscore in cancer prognosis and therapeutic efficacy

D Bruni, HK Angell, J Galon - Nature Reviews Cancer, 2020 - nature.com
Abstract The international American Joint Committee on Cancer/Union for International
Cancer Control (AJCC/UICC) tumour-node-metastasis (TNM) staging system provides the …

[HTML][HTML] Cyclooxygenase-2-Prostaglandin E2 pathway: A key player in tumor-associated immune cells

K Jin, C Qian, J Lin, B Liu - Frontiers in oncology, 2023 - frontiersin.org
Cyclooxygenases-2 (COX-2) and Prostaglandin E2 (PGE2), which are important in chronic
inflammatory diseases, can increase tumor incidence and promote tumor growth and …

Interplay between inflammation and cancer

R Khandia, A Munjal - Advances in protein chemistry and structural biology, 2020 - Elsevier
During the 19th century, for the first time, the linkage between inflammation and cancer was
established. Inflammatory microenvironment is an essential component of the tumor …

Cyclooxygenases and prostaglandins in tumor immunology and microenvironment of gastrointestinal cancer

D Wang, CS Cabalag, NJ Clemons, RN DuBois - Gastroenterology, 2021 - Elsevier
Chronic inflammation is a known risk factor for gastrointestinal cancer. The evidence that
nonsteroidal anti-inflammatory drugs suppress the incidence, growth, and metastasis of …

[HTML][HTML] Polyphenols: immunomodulatory and therapeutic implication in colorectal cancer

AM Mileo, P Nisticò, S Miccadei - Frontiers in immunology, 2019 - frontiersin.org
Polyphenolic compounds, widely present in fruits, vegetables, and cereals, have potential
benefits for human health and are protective agents against the development of …

[HTML][HTML] Colorectal cancer immune infiltrates: significance in patient prognosis and immunotherapeutic efficacy

L Guo, C Wang, X Qiu, X Pu, P Chang - Frontiers in immunology, 2020 - frontiersin.org
Colorectal cancer occurrence and progression involve multiple aspects of host immune
deficiencies. In these events, immune cells vary their phenotypes and functions over time …

Enhanced antitumour response of gold nanostar-mediated photothermal therapy in combination with immunotherapy in a mouse model of colon carcinoma

HH Hsieh, CL Chen, HW Chan, KH Chi… - British Journal of …, 2024 - nature.com
Objectives This study investigated the potential of combining PTT with dendritic cell (DC)-
based immunotherapy and anti-PD-L1 immune checkpoint blockade (ICB) therapy against …

[HTML][HTML] The role of m6A epigenetic modification in the treatment of colorectal cancer immune checkpoint inhibitors

H Tong, H Wei, AO Smith, J Huang - Frontiers in Immunology, 2022 - frontiersin.org
Tumor immunotherapy, one of the efficient therapies in cancers, has been called to the
scientific community's increasing attention lately. Among them, immune checkpoint …

[HTML][HTML] An Activated Dendritic-Cell-Related Gene Signature Indicative of Disease Prognosis and Chemotherapy and Immunotherapy Response in Colon Cancer …

Y Ouyang, M Yu, T Liu, M Suo, J Qiao, L Wang… - International Journal of …, 2023 - mdpi.com
Accumulating evidence has underscored the prognostic value of tumor-infiltrating immune
cells in the tumor microenvironment of colon cancer (CC). In this retrospective study, based …

[HTML][HTML] Constructing a prognostic model for head and neck squamous cell carcinoma based on glucose metabolism related genes

Y Liu, N Liu, X Zhou, L Zhao, W Wei, J Hu… - Frontiers in …, 2023 - frontiersin.org
Background Glucose metabolism (GM) plays a crucial role in cancer cell proliferation, tumor
growth, and survival. However, the identification of glucose metabolism-related genes …