The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

Nutritional and health beneficial properties of saffron (Crocus sativus L): a comprehensive review

T Abu-Izneid, A Rauf, AA Khalil… - Critical reviews in …, 2022 - Taylor & Francis
Saffron (Crocus sativus L., family Iridaceae) is used traditionally for medicinal purpose in
Chinese, Ayurvedic, Persian and Unani medicines. The bioactive constituents such as …

[HTML][HTML] Recent Advances on the Anticancer Properties of Saffron (Crocus sativus L.) and Its Major Constituents

A Lambrianidou, F Koutsougianni, I Papapostolou… - Molecules, 2020 - mdpi.com
Cancer is the second leading cause of death globally with an estimated 9.6 million deaths in
2018 and a sustained rise in its incidence in both developing and developed countries …

[PDF][PDF] Saffron: A potential drug-supplement for severe acute respiratory syndrome coronavirus (COVID) management

AM Husaini, KN Jan, GA Wani - Heliyon, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2 (COVID-19), came as a
significant health care challenge for humans in 2019–20. Based on recent laboratory and …

Saffron improves life and sleep quality, glycaemic status, lipid profile and liver function in diabetic patients: A double‐blind, placebo‐controlled, randomised clinical …

A Tajaddini, N Roshanravan… - … journal of clinical …, 2021 - Wiley Online Library
Abstract Background Type 2 diabetes (T2D) is a metabolic disorder that is related to
hyperglycaemia, hyperlipidaemia and liver dysfunction and has detrimental effects on a …

The effect of saffron (Crocus sativus L.) on glycemia, lipid profile, and antioxidant status in patients with type‐2 diabetes mellitus: A randomized placebo‐controlled …

A Tajaddini, N Roshanravan, M Mobasseri… - Phytotherapy …, 2023 - Wiley Online Library
In the current study, we aimed to investigate the effect of saffron supplementation on
glycemic status, lipid profile, atherogenic indices, and oxidative status in patients with type‐2 …

Antidiabetic potential of saffron and its active constituents

H Yaribeygi, V Zare, AE Butler… - Journal of cellular …, 2019 - Wiley Online Library
The prevalence of diabetes mellitus is growing rapidly worldwide. This metabolic disorder
affects many physiological pathways and is a key underlying cause of a multitude of …

[HTML][HTML] Protective effects of medicinal plant-based foods against diabetes: a review on pharmacology, phytochemistry, and molecular mechanisms

P Ansari, JF Samia, JT Khan, MR Rafi, MS Rahman… - Nutrients, 2023 - mdpi.com
Diabetes mellitus (DM) comprises a range of metabolic disorders characterized by high
blood glucose levels caused by defects in insulin release, insulin action, or both. DM is a …

Redox modulation of stress resilience by Crocus sativus L. for potential neuroprotective and anti-neuroinflammatory applications in brain disorders: From molecular …

M Scuto, S Modafferi, F Rampulla, V Zimbone… - Mechanisms of Ageing …, 2022 - Elsevier
Recent evidence demonstrates that Crocus sativus L.(saffron) counteracts oxidative stress,
mitochondrial dysfunction and neuroinflammation, closely linked to initiation and …

[HTML][HTML] The Potential of Plant-Based Bioactive Compounds on Inhibition of Aflatoxin B1 Biosynthesis and Down-regulation of aflR, aflM and aflP Genes

N Safari, M Mirabzadeh Ardakani, R Hemmati… - Antibiotics, 2020 - mdpi.com
The use of plant extracts in pre-and post-harvest disease management of agricultural crops
to cope with aflatoxin B1 contamination has shown great promise due to their capability in …